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卡介苗诱导的婴儿结核性髋部骨髓炎:病例报告

Calmette-Guérin Vaccine-Induced Tuberculous Hip Osteomyelitis in an Infant: Case report.

作者信息

Al-Azri Mohammed S, Manarang Jazel, Al-Mufargi Yaqoub

机构信息

College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.

Department of Child Health, Royal Hospital, Muscat, Oman.

出版信息

Sultan Qaboos Univ Med J. 2017 Aug;17(3):e358-e362. doi: 10.18295/squmj.2017.17.03.019. Epub 2017 Oct 10.

Abstract

To this day, tuberculosis (TB) continues to pose a significant global health burden. The World Health Organization's Expanded Programme on Immunization (EPI) recommends the Calmette-Guérin (BCG) vaccine for infants to protect against the haematogenous spread of primary TB and other more severe types of TB infection. We report an eight-month-old boy who presented to the Armed Forces Hospital, Muscat, Oman, in 2015 with a one-month history of intermittent fever associated with a limited range of motion in the right hip area. He was up-to-date with his EPI vaccinations and had no history of exposure to individuals with TB infections. He was initially treated for bacterial septic arthritis; however, a GeneXpert TB assay revealed the presence of , BCG strain. To the best of the authors' knowledge, this is the first documented case from Oman of a child with TB hip osteomyelitis due to a BCG vaccination.

摘要

时至今日,结核病(TB)仍然是全球重大的健康负担。世界卫生组织扩大免疫规划(EPI)建议为婴儿接种卡介苗(BCG),以预防原发性结核病的血行播散及其他更严重类型的结核感染。我们报告一例八个月大的男童,2015年因右髋部活动范围受限伴间歇性发热一个月就诊于阿曼马斯喀特的武装部队医院。他按程序接种了EPI疫苗,且无接触结核感染患者的病史。他最初被诊断为细菌性化脓性关节炎并接受治疗;然而,一项GeneXpert结核检测显示存在卡介苗菌株。据作者所知,这是阿曼首例记录在案的因接种卡介苗导致儿童结核性髋部骨髓炎的病例。

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Calmette-Guérin Vaccine-Induced Tuberculous Hip Osteomyelitis in an Infant: Case report.卡介苗诱导的婴儿结核性髋部骨髓炎:病例报告
Sultan Qaboos Univ Med J. 2017 Aug;17(3):e358-e362. doi: 10.18295/squmj.2017.17.03.019. Epub 2017 Oct 10.
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本文引用的文献

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Tuberculosis of hip: A current concept review.髋关节结核:当前概念综述
Indian J Orthop. 2015 Jan-Feb;49(1):1-9. doi: 10.4103/0019-5413.143903.
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Osteomyelitis of the long bones.长骨骨髓炎。
Semin Plast Surg. 2009 May;23(2):59-72. doi: 10.1055/s-0029-1214158.

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