Diffuse midline gliomas with subclonal H3F3A K27M mutation and mosaic H3.3 K27M mutant protein expression.
作者信息
Lopez Giselle Y, Oberheim Bush Nancy Ann, Phillips Joanna J, Bouffard John-Paul, Moshel Yaron A, Jaeckle Kurt, Kleinschmidt-DeMasters B K, Rosenblum Marc K, Perry Arie, Solomon David A
机构信息
Division of Neuropathology, Department of Pathology, University of California, San Francisco, 513 Parnassus Ave, Health Sciences West 451, Box 0102, San Francisco, CA, 94143, USA.
Division of Neuro-Oncology, Department of Neurological Surgery, University of California, San Francisco, CA, USA.
出版信息
Acta Neuropathol. 2017 Dec;134(6):961-963. doi: 10.1007/s00401-017-1780-0. Epub 2017 Oct 23.
Abstract
摘要
相似文献
1
Diffuse midline gliomas with subclonal H3F3A K27M mutation and mosaic H3.3 K27M mutant protein expression.具有亚克隆H3F3A K27M突变和镶嵌性H3.3 K27M突变蛋白表达的弥漫性中线胶质瘤
Acta Neuropathol. 2017 Dec;134(6):961-963. doi: 10.1007/s00401-017-1780-0. Epub 2017 Oct 23.
2
Incidence and clinicopathologic features of H3 K27M mutations in adults with radiographically-determined midline gliomas.影像学诊断的中线胶质瘤中 H3 K27M 突变的发生率及临床病理特征。
J Neurooncol. 2019 May;143(1):87-93. doi: 10.1007/s11060-019-03134-x. Epub 2019 Mar 12.
3
Diffuse non-midline glioma with H3F3A K27M mutation: a prognostic and treatment dilemma.伴有H3F3A K27M突变的弥漫性非中线胶质瘤：预后与治疗困境
Acta Neuropathol Commun. 2017 May 15;5(1):38. doi: 10.1186/s40478-017-0440-x.
4
Diffuse high-grade gliomas with H3 K27M mutations carry a dismal prognosis independent of tumor location.弥漫性高级别胶质瘤伴 H3 K27M 突变无论肿瘤位置如何，预后均较差。
Neuro Oncol. 2018 Jan 10;20(1):123-131. doi: 10.1093/neuonc/nox149.
5
H3F3A mutant allele specific imbalance in an aggressive subtype of diffuse midline glioma, H3 K27M-mutant.H3F3A 突变等位基因特异性失衡与 H3 K27M 突变弥漫性中线胶质瘤的侵袭性亚型相关。
Acta Neuropathol Commun. 2020 Feb 5;8(1):8. doi: 10.1186/s40478-020-0882-4.
6
Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations.伴组蛋白H3-K27M突变的弥漫性中线胶质瘤：47例病例系列研究，评估形态学变异谱及相关基因改变
Brain Pathol. 2016 Sep;26(5):569-80. doi: 10.1111/bpa.12336. Epub 2015 Dec 14.
7
Noninvasive assessment of H3 K27M mutational status in diffuse midline gliomas by using apparent diffusion coefficient measurements.通过表观扩散系数测量无创评估弥漫性中线胶质瘤 H3 K27M 突变状态。
Eur J Radiol. 2019 May;114:152-159. doi: 10.1016/j.ejrad.2019.03.006. Epub 2019 Mar 14.
8
H3 K27M-mutant diffuse midline gliomas in different anatomical locations.不同解剖部位 H3 K27M 突变型弥漫中线胶质瘤。
Hum Pathol. 2018 Aug;78:89-96. doi: 10.1016/j.humpath.2018.04.015. Epub 2018 May 1.
9
Histone H3 K27M mutations in adult cerebellar high-grade gliomas.成人小脑高级别胶质瘤中的组蛋白H3 K27M突变
Brain Tumor Pathol. 2017 Jul;34(3):113-119. doi: 10.1007/s10014-017-0288-6. Epub 2017 May 25.
10
An adult case of diffuse midline glioma with H3 K27M mutation.弥漫性中线胶质瘤伴 H3 K27M 突变的 1 例成人病例。
Neuropathology. 2020 Dec;40(6):627-631. doi: 10.1111/neup.12689. Epub 2020 Sep 20.
引用本文的文献
1
The prognostic impact of subclonal IDH1 mutation in grade 2-4 astrocytomas.2-4级星形细胞瘤中亚克隆性异柠檬酸脱氢酶1（IDH1）突变的预后影响
Neurooncol Adv. 2023 May 29;5(1):vdad069. doi: 10.1093/noajnl/vdad069. eCollection 2023 Jan-Dec.
2
Imaging features associated with H3 K27-altered and H3 G34-mutant gliomas: a narrative systematic review.与 H3 K27 改变和 H3 G34 突变神经胶质瘤相关的影像学特征：叙述性系统评价。
Cancer Imaging. 2022 Nov 17;22(1):63. doi: 10.1186/s40644-022-00500-3.
3
Diffuse astrocytoma with mosaic -R132H-mutant immuno-phenotype and low subclonal allele frequency.具有镶嵌型-R132H-突变免疫表型和低亚克隆等位基因频率的弥漫性星形细胞瘤
Intractable Rare Dis Res. 2022 Feb;11(1):43-45. doi: 10.5582/irdr.2022.01019.
4
Mosaic Pattern of H3 K27M-Mutant Protein Expression in a Diffuse Midline Glioma-A Diagnostic Dilemma for the Pathologist.弥漫性中线胶质瘤中H3 K27M突变蛋白表达的镶嵌模式——病理学家面临的诊断难题
J Neurosci Rural Pract. 2021 Jul;12(3):596-598. doi: 10.1055/s-0041-1728231. Epub 2021 May 10.
5
Genomic Profiling Identified Novel Prognostic Biomarkers in Chinese Midline Glioma Patients.基因组分析在中国中线胶质瘤患者中鉴定出新型预后生物标志物。
Front Oncol. 2021 Mar 3;10:607429. doi: 10.3389/fonc.2020.607429. eCollection 2020.
6
Current Advances in Immunotherapy for Glioblastoma.胶质母细胞瘤的免疫治疗新进展。
Curr Oncol Rep. 2021 Jan 26;23(2):21. doi: 10.1007/s11912-020-01007-5.
7
Mutations within FGFR1 are associated with superior outcome in a series of 83 diffuse midline gliomas with H3F3A K27M mutations.在83例伴有H3F3A K27M突变的弥漫性中线胶质瘤系列病例中，FGFR1基因内的突变与较好的预后相关。
Acta Neuropathol. 2021 Feb;141(2):323-325. doi: 10.1007/s00401-020-02259-y. Epub 2021 Jan 12.
8
Genomic Landscape of Intramedullary Spinal Cord Gliomas.椎管内脊髓胶质瘤的基因组景观。
Sci Rep. 2019 Dec 10;9(1):18722. doi: 10.1038/s41598-019-54286-9.
9
Alternative lengthening of telomeres, ATRX loss and H3-K27M mutations in histologically defined pilocytic astrocytoma with anaplasia.具有间变特征的组织学定义的毛细胞星形细胞瘤中的端粒的替代性延长、 ATRX 缺失和 H3-K27M 突变。
Brain Pathol. 2019 Jan;29(1):126-140. doi: 10.1111/bpa.12646. Epub 2018 Oct 17.
10
H3 K27M-mutant gliomas in adults vs. children share similar histological features and adverse prognosis.成人与儿童的H3 K27M突变型胶质瘤具有相似的组织学特征和不良预后。
Clin Neuropathol. 2018 Mar/Apr;37 (2018)(2):53-63. doi: 10.5414/NP301085.
本文引用的文献
1
Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.对儿科神经肿瘤患者进行靶向二代测序可改善诊断、识别致病性种系突变并指导靶向治疗。
Neuro Oncol. 2017 May 1;19(5):699-709. doi: 10.1093/neuonc/now254.
2
Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma.弥漫性脑桥内生型胶质瘤中驱动基因突变的时空同质性
Nat Commun. 2016 Apr 6;7:11185. doi: 10.1038/ncomms11185.
3
Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics.弥漫性内在脑桥和中线高级别神经胶质瘤的空间基因组异质性：对诊断性活检和靶向治疗的影响。
Acta Neuropathol Commun. 2016 Jan 4;4:1. doi: 10.1186/s40478-015-0269-0.
4
Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations.伴组蛋白H3-K27M突变的弥漫性中线胶质瘤：47例病例系列研究，评估形态学变异谱及相关基因改变
Brain Pathol. 2016 Sep;26(5):569-80. doi: 10.1111/bpa.12336. Epub 2015 Dec 14.
5
Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes.组蛋白H3F3A和HIST1H3B K27M突变定义了弥漫性脑桥内在型胶质瘤的两个亚组，它们具有不同的预后和表型。
Acta Neuropathol. 2015 Dec;130(6):815-27. doi: 10.1007/s00401-015-1478-0. Epub 2015 Sep 23.
6
The 2007 WHO classification of tumours of the central nervous system.2007年世界卫生组织中枢神经系统肿瘤分类
Acta Neuropathol. 2007 Aug;114(2):97-109. doi: 10.1007/s00401-007-0243-4. Epub 2007 Jul 6.
Zotero 插件