富血小板血浆、血小板裂解物和胎牛血清对间充质干细胞的比较作用
Comparative Effects of Platelet-Rich Plasma, Platelet Lysate, and Fetal Calf Serum on Mesenchymal Stem Cells.
作者信息
Lykov A P, Bondarenko N A, Surovtseva M A, Kim I I, Poveshchenko O V, Pokushalov E A, Konenkov V I
机构信息
Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, Novosibirsk, Russia.
出版信息
Bull Exp Biol Med. 2017 Oct;163(6):757-760. doi: 10.1007/s10517-017-3897-5. Epub 2017 Oct 24.
We studied the effects of human platelet-rich plasma and platelet lysate on proliferation, migration, and colony-forming properties of rat mesenchymal stem cells. Platelet-rich plasma and platelet lysate stimulated the proliferation, migration, and colony formation of mesenchymal stem cells. A real-time study showed that platelet-rich plasma produces the most potent stimulatory effect, while both platelet-rich plasma and platelet lysate stimulated migration of cells.
我们研究了富含人血小板的血浆和血小板裂解物对大鼠间充质干细胞增殖、迁移及集落形成特性的影响。富含血小板的血浆和血小板裂解物刺激了间充质干细胞的增殖、迁移和集落形成。一项实时研究表明，富含血小板的血浆产生的刺激作用最强，而富含血小板的血浆和血小板裂解物均刺激了细胞的迁移。
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