Ackerson Brad, Thorpe Ryan, W Nicholas Matilda
Department of Dermatology, Duke University Hospital, Durham, NC, USA.
Adv Exp Med Biol. 2017;1027:105-120. doi: 10.1007/978-3-319-64804-0_10.
Atopic dermatitis frequently requires the use of over-the-counter and prescription medications for effective management. Emollients and topical corticosteroids are effective for most patients and are the most commonly utilized agents by experienced dermatologists. Antihistamines, antibiotics, and calcineurin inhibitors may also prove helpful in the correct clinical scenarios. Severe atopic dermatitis, however, can be difficult to manage and not infrequently require substantial immunomodulatory medications. Targeted molecular therapies, such as dupilumab, are promising, emerging atopic dermatitis therapies. The medication pearls reviewed in this chapter will assist providers in managing atopic dermatitis patients.
特应性皮炎通常需要使用非处方和处方药物进行有效管理。润肤剂和外用糖皮质激素对大多数患者有效，并且是经验丰富的皮肤科医生最常用的药物。抗组胺药、抗生素和钙调神经磷酸酶抑制剂在正确的临床情况下也可能有帮助。然而，重度特应性皮炎可能难以管理，并且常常需要大量免疫调节药物。靶向分子疗法，如度普利尤单抗，是有前景的、新兴的特应性皮炎治疗方法。本章回顾的用药要点将有助于医疗服务提供者管理特应性皮炎患者。
