Ghoreishi Mohammad, Naderi Beni Afsaneh, Naderi Beni Zahra, Zandi Alireza, Kianersi Farzan
Department of Ophthalmology, Isfahan University of Medical Science, Isfahan, Iran.
Department of Ophthalmology, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Lasers Med Sci. 2017 Dec;32(9):2129-2138. doi: 10.1007/s10103-017-2357-9. Epub 2017 Oct 23.
The purpose of this study is to compare visual outcomes of myopic refractive surgery, using tissue saving (TS), a standard ablation profile by a Technolas 217z100, and aberration smart ablation (ASA), an aspheric algorithm by a MEL 80 excimer laser in two eyes of one patient. In this prospective interventional paired-eye controlled study, a total of 100 eyes of 50 participants with myopia with or without astigmatism underwent thin-flap Femto-LASIK, using a Femto LDV femtosecond laser (Ziemer Ophthalmic Systems AG, Port, Switzerland). For each patient, one eye was randomly treated with tissue-saving algorithm (TS group) by the Technolas 217z100 excimer laser and the other eye was treated with optimized smart ablation profile (ASA group) by the MEL 80 excimer laser. Outcome measures were uncorrected distance visual acuities (UDVAs), corrected distance visual acuities (CDVAs), manifest refraction, higher-order aberrations (HOAs), contrast sensitivity, and patient satisfaction 12 months after surgery. At 12 months postoperative, "45 subjects returned with mean" UDVA was - 0.02 ± 0.08 Logarithm of mean angle of resolution (LogMAR) for TS group and - 0.02 ± 0.09 LogMAR for ASA group (P = 0.91). Of the TS eyes, 42/45 (93.3%) and 32/45 (71.1%) were within ± 0.5 D and ± 0.25 D of target refraction, respectively, and of the ASA eyes, 41/45 (91.1%) and 30/45 (66.6%) were within ± 0.5 D and ± 0.25 D of target refraction, respectively. No statistically significant differences were observed between groups in HOAs changes and contrast sensitivity function. Aspheric and non-aspheric LASIKs using the two different excimer lasers provide similar results in myopic and myopic astigmatism patients.
本研究的目的是比较在同一名患者的双眼上，使用Technolas 217z100的标准消融模式（组织保存，TS）和MEL 80准分子激光的非球面算法（像差智能消融，ASA）进行近视屈光手术的视觉效果。在这项前瞻性干预性双眼对照研究中，共有50名近视患者（有或无散光）的100只眼睛接受了薄瓣飞秒激光原位角膜磨镶术（Femto-LASIK），使用的是Femto LDV飞秒激光（齐默眼科系统股份公司，瑞士波特）。对于每位患者，一只眼睛随机采用Technolas 217z100准分子激光的组织保存算法进行治疗（TS组），另一只眼睛采用MEL 80准分子激光的优化智能消融模式进行治疗（ASA组）。观察指标为术后12个月时的裸眼远视力（UDVA）、矫正远视力（CDVA）、显验光、高阶像差（HOA）、对比敏感度和患者满意度。术后12个月时，“45名受试者回访，TS组的平均”UDVA为-0.02±0.08平均角分辨率对数（LogMAR），ASA组为-0.02±0.09 LogMAR（P = 0.91）。在TS组眼中，分别有42/45（93.3%）和32/45（71.1%）在目标屈光度的±0.5 D和±0.25 D范围内；在ASA组眼中，分别有41/45（91.1%）和30/45（66.6%）在目标屈光度的±0.5 D和±0.25 D范围内。两组在高阶像差变化和对比敏感度函数方面未观察到统计学上的显著差异。使用两种不同准分子激光的非球面和非非球面LASIK在近视和近视散光患者中提供了相似的结果。
