Zhongshan Ophthalmic Center and State Key Laboratory of Ophthalmology, Hainan Eye Hospital, Sun Yat-sen University, Guangzhou, China.
J Cataract Refract Surg. 2013 Jul;39(7):1059-65. doi: 10.1016/j.jcrs.2013.01.043.
To compare the effects of a combined wavefront-guided and aspheric ablation profile with an aspheric ablation profile alone to correct myopia in patients with a preoperative total higher-order aberration root mean square (HOA RMS) lower than 0.30 μm in both eyes.
Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Comparative case series.
Laser in situ keratomileusis was performed, with 1 eye randomized to wavefront-guided with aspheric ablation and the fellow eye to aspheric ablation only. The uncorrected (UDVA) and corrected (CDVA) distance visual acuities, manifest subjective refraction, corneal topography, RMS value of total and grouped HOAs, and contrast sensitivity were measured preoperatively and 1 and 6 months postoperatively.
The study enrolled 62 eyes (31 patients). The increasing factors of total HOA RMS, 3rd-order RMS and 4th-order RMS were 2.09, 2.09, and 1.99, respectively, in the wavefront-guided with aspheric ablation group and 2.52, 2.68, and 2.51, respectively, in the aspheric ablation only group at 6 months; the aspheric ablation group had statistically significantly larger increasing factors (P=.016, P=.038, and P=.027, respectively). The reduction in contrast sensitivity log values was statistically significantly less in the wavefront-guided with aspheric ablation group than in the aspheric ablation only group except at 1.5 cycles per degree.
The wavefront-guided with aspheric ablation profile was associated with better limitation of HOAs and faster recovery of mesopic contrast sensitivity for patients with a preoperative total HOA RMS lower than 0.30 μm.
No author has a financial or proprietary interest in any material or method mentioned.
比较联合波前引导和非球面切削模式与单纯非球面切削模式矫正双眼术前总高阶像差均方根（HOA RMS）值均低于 0.30μm 的近视患者的效果。
中山大学中山眼科中心，中国广州。
对比病例系列研究。
进行准分子激光原位角膜磨镶术，1 只眼随机采用波前引导联合非球面切削，另 1 只眼单纯采用非球面切削。术前及术后 1 个月和 6 个月测量未矫正（UDVA）和矫正（CDVA）远视力、主观验光、角膜地形图、总高阶像差和分组高阶像差 RMS 值以及对比敏感度。
本研究共纳入 62 只眼（31 例患者）。波前引导联合非球面切削组术后 6 个月总 HOA RMS、3 阶 RMS 和 4 阶 RMS 的增加因子分别为 2.09、2.09 和 1.99，单纯非球面切削组分别为 2.52、2.68 和 2.51，差异有统计学意义（P=.016、P=.038 和 P=.027）。波前引导联合非球面切削组对比敏感度 log 值的下降幅度显著小于单纯非球面切削组，除在 1.5 周/度时差异无统计学意义。
对于术前总 HOA RMS 值低于 0.30μm 的患者，波前引导联合非球面切削模式可更好地限制高阶像差，更快地恢复中值对比敏感度。
无相关财务披露。
