Romanoff Anya, Nulsen Benjamin, Mester Jolinda, Jaffer Shabnam, Weltz Christina
Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Department of Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Breast J. 2018 May;24(3):356-359. doi: 10.1111/tbj.12936. Epub 2017 Oct 24.
Patients presenting with pathologic nipple discharge (PND) often pose a diagnostic and therapeutic challenge. We used ultrasound to identify focal ductal dilatation-hypothesized to be a radiographic manifestation of the causative lesion-in patients with PND and no relevant clinical or radiographic findings. Twenty-two excisions guided by ultrasound wire localization of focal duct dilation were performed. Surgical pathology revealed papilloma in 20 cases (91%); atypia or carcinoma was detected in 7 cases (32%). The ultrasound finding of focal duct dilatation enables excision of otherwise occult though clinically significant lesions and is worthy of further study.
出现病理性乳头溢液（PND）的患者常常带来诊断和治疗方面的挑战。我们利用超声来识别局灶性导管扩张——假定为病因性病变的影像学表现——在无相关临床或影像学发现的PND患者中。对22例通过超声引导下局灶性导管扩张钢丝定位进行了切除手术。手术病理显示20例（91%）为乳头状瘤；7例（32%）检测到异型性或癌。局灶性导管扩张的超声表现能够切除临床上虽不明显但具有重要意义的隐匿性病变，值得进一步研究。
