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帕金森病患者在服用和未服用多巴胺能药物时塞音发音的发声对比。

Voicing contrast of stop consonant production in the speech of individuals with Parkinson disease ON and OFF dopaminergic medication.

作者信息

Whitfield Jason A, Reif Angela, Goberman Alexander M

机构信息

a Department of Communication Sciences and Disorders , Bowling Green State University , Bowling Green , OH , USA.

b School of Speech-Language Pathology and Audiology , University of Akron , Akron , OH , USA.

出版信息

Clin Linguist Phon. 2018;32(7):587-594. doi: 10.1080/02699206.2017.1387816. Epub 2017 Oct 24.

DOI:10.1080/02699206.2017.1387816
PMID:29064294
Abstract

The aims of this study were to: 1) compare voicing contrast in speakers with Parkinson disease (PD) and healthy controls by comparing the separation of voice onset time (VOT) distributions of voiced and voiceless stop consonants and 2) to determine whether the administration of dopaminergic medication affected VOT separation in speakers with PD. Data from a previous study by Fisher and Goberman (2010) were used to compare the VOT measures obtained from a group of speakers with PD with both ON and OFF medication, and a group of healthy controls. Supplementing the previous findings, the current analysis revealed that individuals with PD exhibited significantly less contrast between voiced and voiceless VOT than that observed in healthy speakers. Medication administration did not affect VOT contrast as no differences in VOT separation were observed between the ON and OFF medication states.

摘要

本研究的目的是

1)通过比较浊音和清音塞音的语音起始时间(VOT)分布的分离情况,比较帕金森病(PD)患者与健康对照者的浊音对比;2)确定多巴胺能药物的给药是否会影响PD患者的VOT分离。Fisher和Goberman(2010)先前一项研究的数据被用于比较一组服用和未服用药物的PD患者以及一组健康对照者的VOT测量结果。作为对先前研究结果的补充,当前分析表明,PD患者的浊音和清音VOT之间的对比明显低于健康受试者。药物给药并未影响VOT对比,因为在服药和未服药状态之间未观察到VOT分离的差异。

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Clin Linguist Phon. 2018;32(7):587-594. doi: 10.1080/02699206.2017.1387816. Epub 2017 Oct 24.
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