Misiewicz J J
Dept. of Gastroenterology and Nutrition, Central Middlesex Hospital, London, U.K.
Scand J Gastroenterol Suppl. 1988;146:175-84. doi: 10.3109/00365528809099144.
Future trends in the short- and long-term management of peptic ulcer disease are considered. The present state of development of pharmacologic agents for the short-term healing of duodenal and gastric ulcer is impressive, and high rates of healing with rapid symptom relief can be safely achieved with several agents. The problem of ulcer recurrence has not been solved, although new work concerning the role of Campylobacter pylori holds promise. The mortality of acute gastrointestinal haemorrhage remains unacceptably high, especially in the elderly. Therapeutic endoscopy may be effective in decreasing the death rate from bleeding.
本文探讨了消化性溃疡疾病短期和长期管理的未来趋势。用于十二指肠和胃溃疡短期愈合的药物制剂的当前发展状况令人印象深刻，几种药物能够安全地实现高愈合率并迅速缓解症状。尽管有关幽门弯曲杆菌作用的新研究颇具前景，但溃疡复发问题仍未得到解决。急性胃肠道出血的死亡率仍然高得令人无法接受，尤其是在老年人中。治疗性内镜检查可能有助于降低出血死亡率。
