Department of Chemical Engineering, †Department of Chemistry, The Pennsylvania State University , University Park, Pennsylvania 16802, United States.
J Am Chem Soc. 2017 Nov 8;139(44):15588-15591. doi: 10.1021/jacs.7b08783. Epub 2017 Oct 24.
Chemotaxis provides a mechanism for directing the transport of molecules along chemical gradients. Here, we show the chemotactic migration of dye molecules in response to the gradients of several different neutral polymers. The magnitude of chemotactic response depends on the structure of the monomer, polymer molecular weight and concentration, and the nature of the solvent. The mechanism involves cross-diffusion up the polymer gradient, driven by favorable dye-polymer interaction. Modeling allows us to quantitatively evaluate the strength of the interaction and the effect of the various parameters that govern chemotaxis.
趋化作用为分子沿着化学梯度的定向输运提供了一种机制。在这里，我们展示了染料分子在几种不同中性聚合物梯度下的趋化运动。趋化反应的幅度取决于单体结构、聚合物分子量和浓度以及溶剂的性质。该机制涉及沿聚合物梯度的交叉扩散，由有利的染料-聚合物相互作用驱动。通过建模，我们可以定量评估相互作用的强度以及控制趋化作用的各种参数的影响。
