Albathi Monirah, Agrawal Yuri
Department of Otolaryngology-Head and Neck Surgery, School of Medicine, School of Public Health, The Johns Hopkins University, Baltimore, MD, USA.
Department of Surgery, College of Medicine, Princess Nourah University Riyadh, Riyadh, Saudi Arabia.
J Vestib Res. 2017;27(2-3):127-135. doi: 10.3233/VES-170617.
BACKGROUND/OBJECTIVE: Several small studies in animals and humans have suggested a relationship between vestibular function and sleep. In this study, we evaluate the association between vestibular vertigo and sleep duration in a large, representative sample of US adults.
We used data from the National Health Interview Survey, which administered a Balance Supplement in 2008 in a sample of 20,950 adult respondents. We evaluated the cross-sectional association between vestibular vertigo (based on a well-validated definition) and sleep duration (defined as short <6 hours, normal 6-8 hours, and long >8 hours). We performed multiple and multinomial logistic regression analyses to estimate the odds ratio and relative risk ratio (RRR) of impaired sleep duration compared to normal sleep duration associated with vestibular vertigo. Analyses were adjusted for demographic, lifestyle and health behavior characteristics as well as relevant comorbid conditions.
Thirty percent of individuals with vestibular vertigo reported abnormal sleep duration (15.5% short duration and 14.8% long duration). In adjusted analyses, individuals with vestibular vertigo had a 1.75 (95% CI 1.45-2.11) RRR of having short sleep duration compared to individuals without vestibular vertigo, and a 1.55 (95% CI 1.26-1.91) RRR of having long sleep duration compared to individuals without vestibular vertigo.
This study presents epidemiologic evidence to support the association between vestibular function and sleep duration. Individuals with vestibular vertigo had a higher RRR for abnormally short or long sleep duration. Further work is needed to evaluate the causal direction(s) of this association.
背景/目的：多项针对动物和人类的小型研究表明前庭功能与睡眠之间存在关联。在本研究中，我们在一个具有代表性的美国成年人大样本中评估前庭性眩晕与睡眠时间之间的关联。
我们使用了来自美国国家健康访谈调查的数据，该调查在2008年对20950名成年受访者的样本进行了平衡补充调查。我们评估了前庭性眩晕（基于经过充分验证的定义）与睡眠时间（定义为短睡眠<6小时、正常睡眠6 - 8小时和长睡眠>8小时）之间的横断面关联。我们进行了多项和多项逻辑回归分析，以估计与前庭性眩晕相关的睡眠时长受损与正常睡眠时长相比的优势比和相对风险比（RRR）。分析对人口统计学、生活方式和健康行为特征以及相关合并症进行了调整。
30%的前庭性眩晕患者报告睡眠时长异常（15.5%为短睡眠时长，14.8%为长睡眠时长）。在调整分析中，与无前庭性眩晕的个体相比，前庭性眩晕患者短睡眠时长的RRR为1.75（95%CI 1.45 - 2.11），长睡眠时长的RRR为1.55（95%CI 1.26 - 1.91）。
本研究提供了流行病学证据来支持前庭功能与睡眠时间之间的关联。前庭性眩晕患者出现异常短睡眠或长睡眠时长的RRR更高。需要进一步开展工作来评估这种关联的因果方向。
