在接受行为疗法的不同依从性组中，用于预测遗尿严重程度和治疗反应的行为因素。
Behavioral factors for predicting severity of enuresis and treatment responses in different compliance groups receiving behavioral therapy.
作者信息
Ma Yanli, Liu Xiaomei, Shen Ying
机构信息
Yanli Ma, Department of Nephrology, Beijing Children's Hospital, Capital Medical University, Beijing Key Laboratory of Chronic Kidney Disease andBlood Purification of Children. No.56, South Lishi Road, Xicheng District, Beijing, China.
Xiaomei Liu, Department of Nephrology, Beijing Children's Hospital, Capital Medical University, Beijing Key Laboratory of Chronic Kidney Disease andBlood Purification of Children. No.56, South Lishi Road, Xicheng District, Beijing, China.
出版信息
Pak J Med Sci. 2017 Jul-Aug;33(4):953-958. doi: 10.12669/pjms.334.12922.
OBJECTIVE
To investigate behavioral factors for predicting severity of nocturnal enuresis and compare response rates in different compliance groups of behavioral interventions.
METHODS
Three hundred eleven children diagnosed with nocturnal enuresis were enrolled. This study was conducted at Beijing Children's Hospital affiliated to the Capital Medical University from September 2016 to December 2016. Correlation of severity of enuresis and behavioral factors was investigated. All patients were treated with desmopressin based on behavioral interventions. After twomonth treatment, the patients were grouped according to the compliance of behavioral therapy. Then response rates in different compliance groups were compared.
RESULTS
Multivariate analysis revealed stool frequency, drinking water before going to bed, awaking the child to toilet at night, and appetite were independent risk factors affecting the severity of enuresis. The complete response rate of enuresis and partial response ratein fullcompliance group are higher than thoseof partial compliance and non-compliance group(21.9% 11.3%, 78.1% 59.8%; 21.9% 0%, 78.1% 49.1%; P<0.01). The complete response rate and partial response rate of partial compliance group are higher than those of the non-compliance group (P<0.01).
CONCLUSIONS
Stool frequency, drinking water before going to bed, awaking the child to toilet at night, and appetite are independent predictive factors affecting the severity of enuresis. Good compliance of behavioral interventions may have a crucial role for better therapeutic outcomes.
目的
探讨预测夜间遗尿严重程度的行为因素，并比较行为干预不同依从性组的反应率。
方法
纳入311例诊断为夜间遗尿的儿童。本研究于2016年9月至2016年12月在首都医科大学附属北京儿童医院进行。研究遗尿严重程度与行为因素的相关性。所有患者在行为干预的基础上接受去氨加压素治疗。治疗2个月后，根据行为疗法的依从性对患者进行分组。然后比较不同依从性组的反应率。
结果
多因素分析显示，排便频率、睡前饮水、夜间唤醒孩子排尿和食欲是影响遗尿严重程度的独立危险因素。完全依从组的遗尿完全缓解率和部分缓解率高于部分依从组和不依从组（21.9%对11.3%，78.1%对59.8%；21.9%对0%，78.1%对49.1%；P<0.01）。部分依从组的完全缓解率和部分缓解率高于不依从组（P<0.01）。
结论
排便频率、睡前饮水、夜间唤醒孩子排尿和食欲是影响遗尿严重程度的独立预测因素。行为干预的良好依从性可能对更好的治疗效果起关键作用。
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