Lim Christopher Thiam Seong, Lee Sut Enn
Christopher Thiam Seong Lim, Unit of Nephrology, Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra, Malaysia.
Sut Enn Lee, Department of Medicine, Kajang Hospital, Selangor, Malaysia.
Pak J Med Sci. 2017 Jul-Aug;33(4):1047-1049. doi: 10.12669/pjms.334.13112.
Ralstonia mannitolilytica is a gram negative soil bacterium. Ralstonia infection though rare, has become the emerging nosocomial pathogens in hospital settings. Various clinical manifestations had been described as well as the mode of transmission. Despite its low virulence factor, it is able to survive under harsh condition and this may potentially cause significant morbidity and mortality especially in immunocompromised patients. Outbreak of Ralstonia mannitolilytica infections in the hospital are typically associated with contaminated medical supplies or instruments. We described here a case of Ralstonia mannitolilytica infection in a dialysis patient that occurred during the municipal reservoir water contamination crisis. In this report, we will also describe the behaviour of Ralstonia genus and its 4 main species, namely R. pickettii, R. solanacearum, R. insidiosa, and R. mannitolilytica and the choices of antibiotic therapy based on literature review.
嗜麦芽窄食单胞菌是一种革兰氏阴性土壤细菌。嗜麦芽窄食单胞菌感染虽然罕见，但已成为医院环境中新兴的医院病原体。已经描述了各种临床表现以及传播方式。尽管其毒力因子较低，但它能够在恶劣条件下存活，这可能会导致显著的发病率和死亡率，尤其是在免疫功能低下的患者中。医院内嗜麦芽窄食单胞菌感染的爆发通常与受污染的医疗用品或器械有关。我们在此描述了一例在市政水库水污染危机期间发生的透析患者嗜麦芽窄食单胞菌感染病例。在本报告中，我们还将根据文献综述描述窄食单胞菌属及其4个主要菌种，即皮氏窄食单胞菌、茄科雷尔氏菌、隐秘雷尔氏菌和嗜麦芽窄食单胞菌的特性以及抗生素治疗的选择。
