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患者自控镇痛的发展与临床应用。

The development and clinical use of patient-controlled analgesia.

作者信息

Owen H, Mather L E, Rowley K

机构信息

Department of Anaesthesia and Intensive Care, Flinders Medical Centre, Flinders University of South Australia, Adelaide.

出版信息

Anaesth Intensive Care. 1988 Nov;16(4):437-47. doi: 10.1177/0310057X8801600409.

DOI:10.1177/0310057X8801600409
PMID:2906785
Abstract

Patient-controlled analgesia has successfully made the transition from research tool to clinical acceptability. Reliable and sophisticated patient-controlled analgesia systems are commercially available. The technique has been most used for control of postoperative pain but has been successfully used during labour, after burns and other trauma and in terminal care. Virtually every opioid has been administered by patient-controlled analgesia using almost every route of administration. It is more effective than the traditional techniques of pain control after surgery but is not automatically so. Choice of opioid and the settings chosen for demand dose and lockout interval greatly influence effectiveness. Patient-controlled analgesia requires active participation by the patient but the psychology of patient-controlled analgesia has generally been under-estimated. Patient-controlled analgesia has developed empirically and many assumptions have been made; there is a need for fundamental research.

摘要

患者自控镇痛已成功地从研究工具转变为临床可接受的方法。可靠且精密的患者自控镇痛系统在市场上有售。该技术最常用于控制术后疼痛,但也已成功应用于分娩期间、烧伤及其他创伤后以及临终关怀中。几乎每种阿片类药物都通过患者自控镇痛以几乎每种给药途径进行给药。它比传统的术后疼痛控制技术更有效,但并非必然如此。阿片类药物的选择以及为需求剂量和锁定间隔所设定的参数对有效性有很大影响。患者自控镇痛需要患者积极参与,但患者自控镇痛的心理学因素通常被低估了。患者自控镇痛是凭经验发展起来的,存在许多假设;因此需要进行基础研究。

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引用本文的文献

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2
Patient-controlled sedation.患者自控镇静
Anesth Prog. 1998 Summer;45(3):117-26.
3
A paradigm to investigate the self-regulation of cocaine administration in humans.一种研究人类可卡因使用自我调节的范式。
Psychopharmacology (Berl). 2005 Jul;180(3):436-46. doi: 10.1007/s00213-005-2192-8. Epub 2005 Feb 22.
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Randomised controlled trial of patient controlled analgesia compared with nurse delivered analgesia in an emergency department.急诊科患者自控镇痛与护士给予镇痛的随机对照试验。
Emerg Med J. 2005 Jan;22(1):25-9. doi: 10.1136/emj.2002.004614.
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A protocol to improve analgesia use in the accident and emergency department.一项改善急诊科镇痛药物使用情况的方案。
J Accid Emerg Med. 1996 May;13(3):177-9. doi: 10.1136/emj.13.3.177.
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Comparison between patient-controlled analgesia and intramuscular meperidine after thoracotomy.开胸术后患者自控镇痛与肌内注射哌替啶的比较。
Can J Anaesth. 1993 May;40(5 Pt 1):409-15. doi: 10.1007/BF03009508.
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Patient-controlled analgesia. Pharmacokinetic and therapeutic considerations.患者自控镇痛。药代动力学及治疗方面的考虑。
Clin Pharmacokinet. 1993 Feb;24(2):124-40. doi: 10.2165/00003088-199324020-00003.
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