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破坏性心境失调障碍(DMDD)的患病率及症状病程

Prevalence Rate and Course of Symptoms of Disruptive Mood Dysregulation Disorder (DMDD).

作者信息

Grau Katharina, Plener Paul L, Hohmann Sarah, Fegert Jörg M, Brähler Elmar, Straub Joana

机构信息

1 Department of Child and Adolescent Psychiatry and Psychotherapy, University of Ulm, Germany.

2 Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health Mannheim, University of Heidelberg, Mannheim, Germany.

出版信息

Z Kinder Jugendpsychiatr Psychother. 2018 Jan;46(1):29-38. doi: 10.1024/1422-4917/a000552. Epub 2017 Oct 25.

DOI:10.1024/1422-4917/a000552
PMID:29067863
Abstract

OBJECTIVE

According to DSM-5, Disruptive Mood Dysregulation Disorder (DMDD) is characterized by chronic temper outbursts and irritable moods. So far, little is known about its prevalence rate, course and influence on individual well-being. We assessed the prevalence rates of DMDD symptoms during adulthood and primary school age - the latter retrospectively - and studied their relationship with psychiatric disorders and socioeconomic variables.

METHODS

A total of 2,413 subjects, aged 18-94 years, participated in this population-based, representative study based on self-reports.

RESULTS

12 (0.50 %) subjects reported elevated DMDD symptoms during adulthood, and 19 (0.79 %) reported elevated DMDD symptoms during primary school age. DMDD symptoms were associated with higher rates of depression and anxiety symptoms. Those reporting elevated DMDD symptoms during adulthood were more often single or divorced, and those reporting elevated DMDD symptoms during primary school age were more often childless and unemployed during adulthood compared to subjects without DMDD symptoms.

CONCLUSIONS

DMDD symptoms seem to show a chronic course and go hand in hand with elevated psychiatric symptoms and impaired socioeconomic and demographic status.

摘要

目的

根据《精神疾病诊断与统计手册》第5版(DSM - 5),破坏性心境失调障碍(DMDD)的特征为慢性的情绪爆发和易怒情绪。到目前为止,对其患病率、病程及对个体幸福感的影响知之甚少。我们评估了成年期和小学年龄段(后者为回顾性评估)DMDD症状的患病率,并研究了它们与精神障碍及社会经济变量之间的关系。

方法

共有2413名年龄在18 - 94岁的受试者参与了这项基于自我报告的、具有代表性的人群研究。

结果

12名(0.50%)受试者报告成年期DMDD症状升高,19名(0.79%)报告小学年龄段DMDD症状升高。DMDD症状与更高的抑郁和焦虑症状发生率相关。与没有DMDD症状的受试者相比,报告成年期DMDD症状升高的人更常单身或离婚,而报告小学年龄段DMDD症状升高的人成年期更常无子女且失业。

结论

DMDD症状似乎呈现慢性病程,且与精神症状升高以及社会经济和人口统计学状况受损密切相关。

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