Department of Psychiatry, National Taiwan University and College of Medicine, Taiwan; Department of Psychiatry, Far Eastern Memorial Hospital, Taiwan.
Yale Child Study Center, Yale University School of Medicine, New Haven, CT, USA.
J Affect Disord. 2021 Feb 15;281:485-492. doi: 10.1016/j.jad.2020.12.039. Epub 2020 Dec 15.
We examined correlates, psychiatric comorbidities, and social adjustment difficulties in children with disruptive mood dysregulation disorder (DMDD) from a national epidemiological study in Taiwan.
The sample consisted of 4816 children, who were 3, 5, and 7 graders from schools randomly chosen based on the urbanization level in a recent national survey of childhood mental disorders. Among the 4816 children (2520 boys, 52.3%) interviewed using the Kiddie epidemiologic version of the Schedule for Affective Disorders and Schizophrenia (K-SADS-E) for the DSM-5, 30 children were diagnosed as DMDD (23 boys, 76.7%). They and their parents also reported on the Social Adjustment Inventory for Children and Adolescents (SAICA). We conducted regressions for survey data that controlled for stratification and clustering.
The weighted prevalence of DMDD was 0.3~0.76% in Taiwanese children. Lower parental educational levels, male predominance, higher psychiatric comorbidities, and worse self-report school functions (e.g., more behavioral problems with peers) were observed in children with DMDD than those without. Additional analyses revealed that oppositional defiant disorder (ODD) but not DMDD was related to conduct disorder. Children with ODD with or without DMDD had more problems regarding attitudes toward school, academic performance, and parent-child interaction at home than those with DMDD-only.
Small sample size of DMDD.
DMDD is a rare disorder in the community. Children with DMDD had more psychiatric comorbidities, and subjectively experienced more difficulties than those without. DMDD and ODD both resulted in severe impairment yet in different domains.
我们从台湾的一项全国性流行病学研究中检查了患有破坏性情绪失调障碍 (DMDD) 的儿童的相关性、精神共病和社会适应困难。
该样本由 4816 名儿童组成，他们是来自学校的 3、5 和 7 年级学生，这些学校是根据最近全国儿童精神障碍调查中城市化水平随机选择的。在使用 Kiddie 流行病学版本的 DSM-5 时间表对 4816 名儿童（2520 名男孩，52.3%）进行访谈的儿童中，有 30 名被诊断为 DMDD（23 名男孩，76.7%）。他们和他们的父母还报告了儿童和青少年社会适应量表 (SAICA)。我们对调查数据进行了回归分析，这些数据控制了分层和聚类。
台湾儿童的 DMDD 加权患病率为 0.3%至 0.76%。与没有 DMDD 的儿童相比，DMDD 儿童的父母受教育程度较低、男性居多、精神共病较多、自我报告的学校功能较差（例如，与同龄人交往的行为问题较多）。进一步的分析表明，对立违抗障碍 (ODD) 而不是 DMDD 与品行障碍有关。患有 ODD 合并或不合并 DMDD 的儿童在对学校的态度、学业成绩和亲子互动方面的问题比仅患有 DMDD 的儿童更多。
DMDD 的样本量小。
DMDD 在社区中是一种罕见的疾病。与没有 DMDD 的儿童相比，患有 DMDD 的儿童有更多的精神共病，并且主观上经历更多的困难。DMDD 和 ODD 都会导致严重的障碍，但在不同的领域。
