Martin Claire A, Nunn Laurence, Lambiase Pier D
Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London, EC1A 7BE, UK.
Maidstone and Tunbridge Wells NHS Trust, Hermitage Lane, Maidstone, Kent, ME16 9QQ, UK.
Indian Pacing Electrophysiol J. 2017 Jul-Aug;17(4):113-115. doi: 10.1016/j.ipej.2017.05.006. Epub 2017 May 26.
A young man suffered cardiac arrests with polymorphic ventricular tachycardia (PVT) and ventricular fibrillation (VF) triggered by ventricular premature contractions (PVCs). The arrhythmia was resistant to anti-arrhythmics, so after ICD implantation he underwent successful ablation of the triggering VE beat, which was pace-mapped to the left posterior hemi-fascicle. We review the evidence for the role of the Purkinje network in the initiation and maintenance of PVT and VF, postulating a channelopathy as a possible underlying cause, and provide recommendations for PVC ablation.
一名年轻男性因室性早搏（PVC）引发多形性室性心动过速（PVT）和心室颤动（VF）而发生心脏骤停。心律失常对抗心律失常药物耐药，因此在植入植入式心脏复律除颤器（ICD）后，他成功消融了触发室性早搏，该早搏经起搏标测定位于左后半分支。我们回顾了浦肯野网络在PVT和VF起始及维持中作用的证据，推测通道病可能是潜在病因，并提供了PVC消融的建议。
