Department of Dermatology, Fukushima Medical University, Fukushima, Japan.
J Dermatol. 2018 Feb;45(2):194-197. doi: 10.1111/1346-8138.14069. Epub 2017 Oct 25.
Lupus alopecia is usually difficult to treat. We report a case of a 40-year-old woman with Sjögren's syndrome and atopic dermatitis who presented with discoid lupus erythematosus on the forearms and lupus erythematosus profundus with alopecia involving the scalp. A biopsy specimen taken from the discoid lupus erythematosus lesion on the forearm further exhibited a xanthomatous reaction, which however was not detected in another specimen from the lupus erythematosus profundus on the scalp. Treatment with oral hydroxychloroquine showed dramatic effects and complete hair regrowth was obtained 3 months later.
狼疮性脱发通常难以治疗。我们报告了一例 40 岁女性，患有干燥综合征和特应性皮炎，前臂出现盘状红斑狼疮，头皮出现深部狼疮性红斑伴脱发。取自前臂盘状红斑狼疮皮损的活检标本进一步显示出黄色瘤反应，但头皮深部狼疮性红斑的另一标本中未检测到。口服羟氯喹治疗显示出显著效果，3 个月后获得了完全的毛发再生。
