Hordinsky Maria
Department of Dermatology, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Dermatol Ther. 2008 Jul-Aug;21(4):245-8. doi: 10.1111/j.1529-8019.2008.00205.x.
Chronic cutaneous lupus erythematosus consists of three major dermatologic diseases: discoid lupus erythematosus (DLE), lupus panniculitis/lupus profundus, and lupus tumidus (Table 1). DLE is estimated to be responsible for 50-85% of patients with chronic cutaneous lupus erythematosus. Scalp involvement is most often the presenting symptom. The clinical features and diagnosis of DLE, its pathophysiology and treatment, are reviewed.
盘状红斑狼疮(DLE)、狼疮性脂膜炎/深部狼疮和肿胀性狼疮(表1)。据估计,50%-85%的慢性皮肤型红斑狼疮患者由DLE引起。头皮受累最常为首发症状。本文对DLE的临床特征、诊断、病理生理学及治疗进行了综述。