Garrocho-Rangel Arturo, Quintana-Guevara Karina, Vázquez-Viera Rocío, Arvizu-Rivera Juana María, Flores-Reyes Héctor, Escobar-García Diana María, Pozos-Guillén Amaury
Associate professor, in the Pediatric Dentistry Postgraduate Program, in the Faculty of Dentistry, San Luis Potosi University, San Luis Potosí, SLP, México.
Resident, in the Pediatric Dentistry Postgraduate Program, in the Faculty of Dentistry, San Luis Potosi University, San Luis Potosí, SLP, México.
Pediatr Dent. 2017 Sep 15;39(5):377-382.
The purpose of this study was to evaluate the clinical and radiographic outcomes of a bioactive tricalcium silicate [Ca3SiO5]-based dentin substitute and a light-activated calcium hydroxide [Ca(OH)2]-based liner as indirect pulp treatment (IPT) interventions for vital primary molars with carious lesions approaching the pulp.
Eighty children, aged four to eight years old, with 160 bilateral primary teeth without signs or symptoms of irreversibly inflamed or degenerative pulp tissue were treated in a split-mouth design trial comparing IPT using Ca3SiO5 or Ca(OH)2. The teeth were treated and restored with a preformed crown in a single session and assessed clinically and radiographically for one, three, six, and 12 months.
Sixty patients with 120 treated molars completed the 12-month evaluations. The combined clinical and radiographic success rates were 98.3 percent (59 out of 60) for Ca3SiO5 and 95 percent for Ca(OH)2 (57 out of 60). No significant differences were found for success rates between the two study groups (P>0.05). The combined success rates for both groups was 96.7 percent.
These results suggest that the indirect pulp treatment procedure with either a bioactive Ca3SiO5-based dentin substitute or a Ca(OH)2-based material may be considered a suitable treatment to achieve acceptable therapeutic results when applied on deeply carious primary teeth without degenerative symptoms.
本研究旨在评估一种基于生物活性硅酸三钙[Ca3SiO5]的牙本质替代物和一种基于光活化氢氧化钙[Ca(OH)2]的垫底材料作为间接盖髓治疗（IPT）干预措施，用于治疗龋损接近牙髓的活髓乳磨牙的临床和影像学结果。
80名4至8岁的儿童，共160颗双侧乳牙，无不可逆性炎症或牙髓组织退变的体征或症状，采用分口设计试验进行治疗，比较使用Ca3SiO5或Ca(OH)2进行间接盖髓治疗的效果。牙齿在单次就诊时进行治疗并使用预成冠修复，并在1、3、6和12个月时进行临床和影像学评估。
60名患者的120颗治疗磨牙完成了12个月的评估。Ca3SiO5组的临床和影像学综合成功率为98.3%（60颗中的59颗），Ca(OH)2组为95%（60颗中的57颗）。两个研究组之间的成功率无显著差异（P>0.05）。两组的综合成功率为96.7%。
这些结果表明，当应用于无退变症状的深龋乳牙时，使用基于生物活性Ca3SiO5的牙本质替代物或基于Ca(OH)2的材料进行间接盖髓治疗可能被认为是一种合适的治疗方法，可取得可接受的治疗效果。
