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2011 年日本静脉血栓栓塞症的发病情况、特征及处理方法。

Incidence, Characteristics and Management of Venous Thromboembolism in Japan During 2011.

机构信息

Department of Cardiology, Suzuka General Hospital.

Department of Cardiology and Nephrology, Mie University Graduate School of Medicine.

出版信息

Circ J. 2018 Jan 25;82(2):555-560. doi: 10.1253/circj.CJ-17-0579. Epub 2017 Oct 25.

Abstract

BACKGROUND

This study aimed to determine the incidence, characteristics and management of venous thromboembolism (VTE) in Japan during 2011.Methods and Results:A retrospective study assessed responses to a questionnaire regarding treating newly diagnosed VTE at all admitting hospitals throughout Japan during 2011. More individuals were diagnosed with VTE than ever before, with 16,096 cases of diagnosed pulmonary embolism (PE) and 24,538 cases of diagnosed deep vein thrombosis (DVT). Almost half (47.2%) of the PE patients had a relatively mild condition with no right ventricular overload. Similarly, almost half (43.8%) of the DVT patients had a relatively mild condition with isolated calf thrombus. Most of PE patients were treated by anticoagulation, and fewer were treated using thrombolytic agent or inferior vena cava (IVC) filter.

CONCLUSIONS

The present study showed a remarkable increase in the incidence of VTE in Japan during 2011. Relatively mild conditions such as non-massive PE and isolated calf DVT were frequently diagnosed. Among PE patients, thrombolytic therapy or IVC filter implantation decreased compared with previous surveys. The appropriate management of isolated calf DVT requires further investigation.

摘要

背景

本研究旨在确定 2011 年日本静脉血栓栓塞症(VTE)的发生率、特征和管理方法。

方法和结果

一项回顾性研究评估了 2011 年日本所有住院医院新诊断 VTE 治疗情况的问卷调查结果。与以往相比,诊断出的 VTE 患者人数有所增加,其中诊断为肺栓塞(PE)的患者为 16096 例,诊断为深静脉血栓形成(DVT)的患者为 24538 例。几乎一半(47.2%)的 PE 患者病情相对较轻,没有右心室超负荷。同样,近一半(43.8%)的 DVT 患者病情相对较轻,仅存在小腿血栓。大多数 PE 患者接受抗凝治疗,较少使用溶栓药物或下腔静脉(IVC)滤器。

结论

本研究表明,2011 年日本 VTE 的发病率显著增加。经常诊断出非大面积 PE 和孤立性小腿 DVT 等相对较轻的情况。与以往的调查相比,PE 患者的溶栓治疗或 IVC 滤器植入减少。孤立性小腿 DVT 的适当治疗需要进一步研究。

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