Rowswell Huw Raymond, Nokes Timothy J C
Department of Haematology, Plymouth Hospitals NHS Trust, Plymouth, UK.
Open Heart. 2017 Sep 28;4(2):e000653. doi: 10.1136/openhrt-2017-000653. eCollection 2017.
Since 2010, National Health Service hospitals in England have been incentivised to risk assess for Venous Thromboembolism (VTE) in all adult patients admitted, using a national tool. We studied the impact of this, together with local real-time reporting of VTE events to senior clinicians, on cases of hospital-acquired thrombosis (HAT) diagnosed, since 2010.
This was an observational cohort study reviewing all cases of VTE diagnosed between January 2010 and December 2016 in a single teaching hospital. These were matched against the number of patients admitted to produce crude incidence rates per thousand admissions. Similarly, all cases associated with inadequate thromboprophylaxis (TP) measures were documented over the same period.
By the end of 2010, with 70% compliance with VTE risk assessment, improving to 90% (the national target) early in 2011, there were 217 HAT events from 103 845 admissions. In 2016, there were 176 HAT events from 119 128 admissions, being a significant reduction, relative risk (RR) 0.718 (95% CI 0.589 to 0.875; p=0.001). In 2010, there were 50 of 217 HAT events associated with inadequate TP, falling to 7 of 176 in 2016, also a significant reduction, RR 0.140 (95% CI 0.065 to 0.300; p=0.0001).
National guidance on VTE prevention and mandatory risk assessment linked to local real-time reporting of VTE events are associated with significant reductions both in total HAT events and those associated with inadequate TP.
自2010年以来,英国国民医疗服务体系(NHS)的医院一直受到激励,要使用一种全国性工具对所有成年住院患者进行静脉血栓栓塞症(VTE)风险评估。我们研究了自2010年以来,这一举措以及向资深临床医生进行VTE事件的本地实时报告,对确诊的医院获得性血栓形成(HAT)病例的影响。
这是一项观察性队列研究,回顾了2010年1月至2016年12月期间在一家教学医院确诊的所有VTE病例。将这些病例与入院患者数量进行匹配,以得出每千例入院患者的粗发病率。同样,在同一时期记录了所有与血栓预防(TP)措施不足相关的病例。
到2010年底,VTE风险评估的依从率为70%,到2011年初提高到90%(全国目标),在103845例入院患者中有217例HAT事件。2016年,在119128例入院患者中有176例HAT事件,显著减少,相对风险(RR)为0.718(95%置信区间0.589至0.875;p = 0.001)。2010年,217例HAT事件中有50例与TP措施不足相关,到2016年降至176例中的7例,也显著减少,RR为0.140(95%置信区间0.065至0.300;p = 0.0001)。
关于VTE预防的国家指南以及与VTE事件的本地实时报告相关的强制性风险评估,与HAT事件总数以及与TP措施不足相关的事件显著减少有关。