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尿道板切开的马蒂厄技术与标准管状切开板尿道成形术在远端尿道下裂一期修复中的比较:一项前瞻性随机研究。

Mathieu technique with incision of the urethral plate versus standard tubularised incised-plate urethroplasty in primary repair of distal hypospadias: A prospective randomised study.

作者信息

Khalil Mostafa, Gharib Tarek, El-Shaer Waleed, Sebaey Ahmed, Elmohamady Basheer, Elgamal Khalid

机构信息

Department of Urology, Faculty of Medicine, Benha University, Benha, Egypt.

出版信息

Arab J Urol. 2017 May 19;15(3):242-247. doi: 10.1016/j.aju.2017.03.007. eCollection 2017 Sep.

Abstract

OBJECTIVE

To compare outcomes of the Mathieu incised-plate (Mathieu-IP) technique vs the standard tubularised incised-plate (TIP) technique for primary management of distal hypospadias.

PATIENTS AND METHODS

Between April 2012 and August 2015, 66 patients (aged 15-60 months) with primary distal hypospadias were randomly allocated to two groups. Group 1 included 34 patients who underwent Mathieu-IP repair and Group 2 included 32 patients managed using the TIP technique for primary management of distal hypospadias. Postoperatively, all patients were examined weekly up to 1 month and then at 3 and 6 months. Perioperative data, complications and outcomes of both procedures were statistically analysed and compared.

RESULTS

There were no statistically significant differences in patient demographics between the groups at baseline. There was no statistically significant difference in the mean (SD) operative time between Groups 1 and 2, at 95 (7.6) and 91.2 (8.1) min, respectively. There was no statistically significant difference in the shape of the urine stream at micturition or the neomeatus between the groups postoperatively. The rate of postoperative fistula was significantly higher in Group 2 (TIP) compared to Group 1 (Mathieu-IP), at 18.7% vs 2.9% ( = 0.004). There was no postoperative meatal stenosis in Group 1, which did occur in five patients (15.6%) in Group 2 ( = 0.002).

CONCLUSION

The Mathieu-IP technique appeared to be better than the standard TIP technique with regard to postoperative fistula formation and meatal stenosis, and with acceptable cosmesis.

摘要

目的

比较Mathieu切开-皮瓣(Mathieu-IP)技术与标准管状化切开-皮瓣(TIP)技术对远端尿道下裂进行一期治疗的效果。

患者与方法

2012年4月至2015年8月期间,66例(年龄15 - 60个月)原发性远端尿道下裂患者被随机分为两组。第1组包括34例行Mathieu-IP修复术的患者,第2组包括32例采用TIP技术对远端尿道下裂进行一期治疗的患者。术后,所有患者每周检查直至1个月,然后在3个月和6个月时检查。对两种手术的围手术期数据、并发症及效果进行统计学分析和比较。

结果

两组患者基线时的人口统计学特征无统计学显著差异。第1组和第2组的平均(标准差)手术时间分别为95(7.6)分钟和91.2(8.1)分钟,两组之间无统计学显著差异。术后两组患者排尿时尿流形状或新尿道口情况无统计学显著差异。第2组(TIP)术后瘘管发生率显著高于第1组(Mathieu-IP),分别为18.7%和2.9%(P = 0.004)。第1组无术后尿道口狭窄,第2组有5例患者(15.6%)发生术后尿道口狭窄(P = 0.002)。

结论

在术后瘘管形成和尿道口狭窄方面,Mathieu-IP技术似乎优于标准TIP技术,且美容效果可接受。

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