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改良覆盖岛状皮瓣与马蒂厄尿道成形术治疗远端尿道下裂的比较:一项前瞻性随机研究。

A modified onlay island flap vs. Mathieu urethroplasty for distal hypospadias repair: A prospective randomised study.

作者信息

ElGanainy Ehab O

机构信息

Assiut Urology and Nephrology Hospital, Faculty of Medicine, Assiut University, Assiut, Egypt.

出版信息

Arab J Urol. 2015 Sep;13(3):169-75. doi: 10.1016/j.aju.2015.06.005. Epub 2015 Jul 26.

DOI:10.1016/j.aju.2015.06.005
PMID:26413341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4563012/
Abstract

OBJECTIVE

To compare the outcome of a modified onlay island flap (MOIF) with that of the Mathieu urethroplasty for distal hypospadias repair.

PATIENTS AND METHODS

In a prospective randomised study, 60 patients with coronal, subcoronal and distal penile hypospadias, with a urethral plate width of ⩽6 mm, and minimal or no chordee, underwent either MOIF using a midline longitudinal outer preputial skin flap passed ventrally by penile buttonholing through dartos fascia incision, or a Mathieu urethroplasty. Closed envelopes were used for randomly selecting patients for each procedure. The operative duration, complications, cosmetic outcome, urinary stream and relatives' satisfaction were reported for each procedure.

RESULTS

Preoperative data (patients' age and site of urethral meatus) and operative duration were insignificantly different between the groups (P = 0.653, 0.786 and 0.710, respectively). There were no intraoperative complications in either group. The duration of follow-up was insignificantly different between the groups. Patients treated with the MOIF had a statistically significant lower complication rate (P = 0.036), and a better cosmetic outcome, urinary stream and relatives' satisfaction (P < 0.001 for all).

CONCLUSIONS

The MOIF urethroplasty seemed to be better than the Mathieu urethroplasty in patients with distal hypospadias and narrow urethral plates. Further studies including more patients, and a longer follow-up with an objective evaluation of functional outcome should be encouraged to confirm these early results.

摘要

目的

比较改良覆盖岛状皮瓣(MOIF)与马蒂厄尿道成形术治疗远端尿道下裂的效果。

患者与方法

在一项前瞻性随机研究中,60例冠状沟型、冠状沟下型及阴茎远端型尿道下裂患者,尿道板宽度≤6mm,阴茎弯曲轻微或无阴茎弯曲,接受了以下两种手术之一:采用经阴茎穿透肉膜筋膜切口向腹侧转移的中线纵向外侧包皮皮肤瓣的MOIF手术,或马蒂厄尿道成形术。使用封闭信封随机为每种手术选择患者。报告了每种手术的手术时长、并发症、外观效果、尿流情况及家属满意度。

结果

两组间术前数据(患者年龄和尿道口位置)及手术时长差异无统计学意义(P分别为0.653、0.786和0.710)。两组均无术中并发症。两组间随访时长差异无统计学意义。接受MOIF治疗的患者并发症发生率显著较低(P = 0.036),外观效果、尿流情况及家属满意度更好(所有P均<0.001)。

结论

对于远端尿道下裂且尿道板狭窄的患者,MOIF尿道成形术似乎优于马蒂厄尿道成形术。应鼓励开展纳入更多患者的进一步研究,并进行更长时间的随访以及对功能结局进行客观评估,以证实这些早期结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ff/4563012/c5be09d8ac42/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ff/4563012/7152c37d3d38/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ff/4563012/ff9898b5dc8a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ff/4563012/c5be09d8ac42/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ff/4563012/7152c37d3d38/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ff/4563012/ff9898b5dc8a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ff/4563012/c5be09d8ac42/gr3.jpg

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