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[肾脏疾病患者中β2-微球蛋白放射免疫测定的临床意义]

[Clinical importance of the radioimmunologic determination of beta 2-microglobulin in patients with kidney pathology].

作者信息

Trusov V V, Filimonov M A, Kazakova I A, Marizin S A

出版信息

Ter Arkh. 1988;60(11):117-20.

PMID:2907187
Abstract

High diagnostic significance of beta 2-microglobulin determination by radioimmunoassay in the blood and urine of patients with the main types of renal pathology (chronic glomerulonephritis, chronic pyelonephritis, hemorrhagic fever with the renal syndrome, and diabetic nephropathy) was shown. A study of beta 2-microglobulin level permitted accurate determination of the localization of pathology in the nephron and assessment of a degree of its expression as well as the detection of initial renal functional disorders, assessment of therapeutic efficacy and dynamic observation of renal function in patients with renal pathology.

摘要

放射免疫分析法测定β2-微球蛋白在主要类型肾脏疾病(慢性肾小球肾炎、慢性肾盂肾炎、肾综合征出血热和糖尿病肾病)患者血液和尿液中的含量具有很高的诊断意义。对β2-微球蛋白水平的研究有助于准确确定病理在肾单位中的定位,评估其表达程度,以及检测早期肾功能障碍,评估治疗效果,并对肾脏疾病患者的肾功能进行动态观察。

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