Cao Shun-Shun, Shan Xiao-Ou, Hu Yang-Yang
Department of Endocrinology and Inherited Metabolism of Children, The Second Hospital Affiliated to Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
Center of Reproductive Medicine, The Second Hospital Affiliated to Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
Zhonghua Nan Ke Xue. 2016 Sep;22(9):805-808.
To investigate the influence of unilateral cryptorchidism on the levels of serum anti-müllerian hormone (AMH) and inhibin B in children.
We enrolled 65 patients with unilateral cryptorchidism and 45 healthy children in this study. We measured the length and circumference of the penis, the testis volume in the cryptorchidism side, and the levels of serum AMH and inhibin B at the age of 6 and 12 months, respectively.
Compared with the healthy controls, the patients with unilateral cryptorchidism showed significant decreases at 12 months in serum AMH (［108.06±12.40］ vs ［103.26±17.57］ ng/ml, P<0.05) and inhibin B (［77.43±5.66］ vs ［70.21±5.69］ pg/ml, P<0.05). No statistically significant differences were found in the length and circumference of the penis and the testis volume in the cryptorchidism side at 6 and 12 months (P>0.05), or in the levels of serum AMH and inhibin B at 6 months (P>0.05).
Unilateral cryptorchidism affects the gonadal function of the patient, and orchiopexy should be timely performed in order to reduce its impact.
探讨单侧隐睾症对儿童血清抗苗勒管激素（AMH）和抑制素B水平的影响。
本研究纳入65例单侧隐睾症患儿和45例健康儿童。分别于6个月和12个月时测量阴茎长度和周长、隐睾侧睾丸体积以及血清AMH和抑制素B水平。
与健康对照组相比，单侧隐睾症患儿在12个月时血清AMH（［108.06±12.40］对［103.26±17.57］ng/ml，P<0.05）和抑制素B（［77.43±5.66］对［70.21±5.69］pg/ml，P<0.05）显著降低。6个月和12个月时阴茎长度和周长以及隐睾侧睾丸体积差异无统计学意义（P>0.05），6个月时血清AMH和抑制素B水平差异也无统计学意义（P>0.05）。
单侧隐睾症影响患儿性腺功能，应及时行睾丸固定术以减轻其影响。
