Zhu Wen-Zuo, Li Gang, Li Kui
Department of Urology, Yucheng People's Hospital, Yucheng, Shandong 251200, China.
Zhonghua Nan Ke Xue. 2016 Sep;22(9):813-816.
To evaluate the influence of the resected prostate tissue volume (RPV) on the improvement of International Prostate Symptom Score (IPSS), quality of life (QOL), and voiding function after transurethral resection of the prostate (TURP).
This study included 82 men with benign prostatic hyperplasia treated by TURP. Before and three months after TURP, we obtained the IPSS, QOL score, post-voiding residual urine volume (PVR), and maximum urinary flow rate (Qmax) from the patients. We measured the total prostate volume (TPV) and transition zone volume (TZV) by transrectal ultrasound preoperatively and investigate the influence of the RPV, RPV/TZV ratio, and RPV/TPV ratio on the efficiency of TURP.
At three months after TURP, the mean Qmax increased by 9.27 ml/s, IPSS decreased by 15.86, QOL score increased by 3.47, PVR decreased by 87.1 ml, and 72.0% of the patients felt satisfied with the surgical results. There was no statistically significant difference in RPV between the patients satisfied and those dissatisfied with the results. Both the RPV/TPV and RPV/TZV ratios significantly increased in the satisfaction group as compared with the dissatisfaction group (P=0.002 and P=0.004). The areas under the ROC curve for the RPV/TPV and RPV/TZV ratios were 0.793 (P=0.001) and 0.687 (P=0.009), respectively.
RPV is closely related to the short-term outcomes of TURP, and the ratios of RPV/TPV and RPV/TZV may be used as new markers to predict the outcomes of TURP.
评估经尿道前列腺切除术(TURP)后切除的前列腺组织体积(RPV)对国际前列腺症状评分(IPSS)、生活质量(QOL)及排尿功能改善的影响。
本研究纳入82例接受TURP治疗的良性前列腺增生男性患者。在TURP术前及术后3个月,获取患者的IPSS、QOL评分、排尿后残余尿量(PVR)及最大尿流率(Qmax)。术前通过经直肠超声测量前列腺总体积(TPV)及移行区体积(TZV),并研究RPV、RPV/TZV比值及RPV/TPV比值对TURP疗效的影响。
TURP术后3个月,平均Qmax增加9.27 ml/s,IPSS降低15.86,QOL评分增加3.47,PVR降低87.1 ml,72.0%的患者对手术结果感到满意。对手术结果满意和不满意的患者之间RPV无统计学显著差异。与不满意组相比,满意组的RPV/TPV和RPV/TZV比值均显著升高(P = 0.002和P = 0.004)。RPV/TPV和RPV/TZV比值的ROC曲线下面积分别为0.793(P = 0.001)和0.687(P = 0.009)。
RPV与TURP的短期疗效密切相关,RPV/TPV和RPV/TZV比值可作为预测TURP疗效的新指标。