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阻力指数:良性前列腺增生患者经尿道前列腺切除术结局的新预测指标。

Resistive index: a newly identified predictor of outcome of transurethral prostatectomy in patients with benign prostatic hyperplasia.

机构信息

Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.

出版信息

Urology. 2010 Jan;75(1):143-7. doi: 10.1016/j.urology.2009.08.017. Epub 2009 Oct 24.

DOI:10.1016/j.urology.2009.08.017
PMID:19854491
Abstract

OBJECTIVE

To examine the usefulness of several preoperative parameters obtained through transrectal ultrasonography in predicting the outcome of transurethral resection of the prostate (TURP).

METHODS

A total of 572 men aged 51-85 years scheduled to undergo TURP for benign prostatic hyperplasia were prospectively enrolled, and 560 were ultimately evaluated. We preoperatively assessed International Prostate Symptom Score (IPSS), quality of life (QOL) score, maximum urinary flow rate (Q(max)), and postvoid residual urine volume (PVR), and measured total prostate volume (TPV), transition zone (TZ) index, and resistive index (RI) using transrectal ultrasonography. To compare the usefulness of the latter 3 indices, we calculated the area under the receiver operating characteristic (ROC) curve for each index and for IPSS.

RESULTS

IPSS (total, postmicturition symptoms, storage symptoms, voiding symptoms), QOL score, Q(max), and PVR were significantly improved after TURP. Significant differences between the effective and noneffective groups were observed with regard to age, IPSS (total, postmicturition symptoms, storage symptoms, voiding symptoms), QOL score, TPV, TZ index, RI, Q(max), and PVR. The area under the ROC curve was 0.663 for IPSS, 0.691 for TPV, 0.719 for the TZ index, and 0.845 for the RI.

CONCLUSIONS

The RI is a useful predictor of an effective outcome after TURP in patients with benign prostatic hyperplasia and may be useful for determining suitability for surgical intervention.

摘要

目的

探讨经直肠超声检查获得的几种术前参数在预测经尿道前列腺切除术(TURP)效果中的作用。

方法

前瞻性纳入 572 名年龄 51-85 岁因良性前列腺增生行 TURP 的男性患者,最终有 560 名患者完成评估。术前评估国际前列腺症状评分(IPSS)、生活质量评分(QOL)、最大尿流率(Qmax)和剩余尿量(PVR),经直肠超声检查测量前列腺总容积(TPV)、移行区指数(TZ 指数)和阻力指数(RI)。为比较后 3 项指数的作用,计算了各指数和 IPSS 的受试者工作特征曲线(ROC)下面积。

结果

TURP 后 IPSS(总分、排尿后症状、储尿症状、排尿症状)、QOL 评分、Qmax 和 PVR 均显著改善。有效组与无效组在年龄、IPSS(总分、排尿后症状、储尿症状、排尿症状)、QOL 评分、TPV、TZ 指数、RI、Qmax 和 PVR 方面存在显著差异。IPSS 的 ROC 曲线下面积为 0.663,TPV 为 0.691,TZ 指数为 0.719,RI 为 0.845。

结论

RI 是预测 TURP 治疗良性前列腺增生患者效果的有用指标,有助于判断是否适合手术干预。

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