Sindhura H, Harsha R H, Shilpa R H
Department of Periodontology, Crown and Bridge, Navodaya Dental College and Hospital, Raichur, Karnataka, India.
Department of Prosthodontics, Crown and Bridge, Navodaya Dental College and Hospital, Raichur, Karnataka, India.
Indian J Dent Res. 2017 Sep-Oct;28(5):514-518. doi: 10.4103/ijdr.IJDR_497_15.
To evaluate the effectiveness of subgingival irrigation with 10% povidone-iodine as an adjunct to scaling and root planing (SRP) and to assess the effectiveness of 10% povidone-iodine in reducing periodontal pathogens mainly Porphyromonas gingivalis (Pg) and Aggregatibacter actinomycetemcomitans (Aa).
Sixty patients with chronic periodontitis of mild to moderate type with periodontal pocket depths (PDs) of 4-6 mm were recruited. At baseline, plaque index, gingival index, and bleeding index were assessed. The PD and clinical attachment level were assessed using the Florida probe®. Pooled subgingival plaque samples were collected. Each participant was allocated into 2 arches, maxillary arch received SRP alone and mandibular arch received SRP with 10% of povidone-iodine irrigation at baseline. After 3 months, same clinical parameters were assessed and plaque samples were collected from both arches. The collected plaque samples were evaluated using polymerase chain reaction. Data were analyzed using SPSS software, version 10 and through independent-samples t-test, paired-samples t-test, and repeated measures ANOVA.
At 3 months posttreatment, subgingival irrigation with povidone-iodine together with SRP showed a statistically significant reduction in all the clinical parameters and in levels of Pg and Aa.
In the present study, 10% povidone-iodine irrigation as an adjunct to SRP favored the nonsurgical periodontal therapy, due to its broad-spectrum antimicrobial activity. Hence, it could be considered as an adjunctive treatment approach in the treatment of chronic periodontitis.
评估10%聚维酮碘龈下冲洗作为龈上洁治和根面平整（SRP）辅助治疗的有效性，并评估10%聚维酮碘在减少主要牙周病原体牙龈卟啉单胞菌（Pg）和伴放线聚集杆菌（Aa）方面的有效性。
招募60例轻度至中度慢性牙周炎患者，牙周袋深度（PD）为4 - 6mm。在基线时，评估菌斑指数、牙龈指数和出血指数。使用Florida探针®评估PD和临床附着水平。收集龈下菌斑混合样本。每位参与者被分配到2个牙弓，上颌牙弓在基线时仅接受SRP，下颌牙弓在基线时接受SRP并进行10%聚维酮碘冲洗。3个月后，评估相同的临床参数，并从两个牙弓收集菌斑样本。使用聚合酶链反应评估收集的菌斑样本。使用SPSS软件10版通过独立样本t检验、配对样本t检验和重复测量方差分析对数据进行分析。
治疗后3个月，聚维酮碘龈下冲洗联合SRP在所有临床参数以及Pg和Aa水平上均显示出统计学上的显著降低。
在本研究中，10%聚维酮碘冲洗作为SRP的辅助治疗，因其广谱抗菌活性有利于非手术牙周治疗。因此，它可被视为慢性牙周炎治疗中的一种辅助治疗方法。
