单纯疱疹病毒性眼角膜结膜炎在印度南部患者人群中的临床特征。
Clinical Profile of Herpes Zoster Ophthalmicus in a South Indian Patient Population.
机构信息
a Department of Ocular Inflammation , Vittala International Institute of Ophthalmology & Prabha Eye Clinic and Research Center , Bangalore , India.
b Department of Ocular Inflammation , Narayana Nethralaya , Bangalore , India.
出版信息
Ocul Immunol Inflamm. 2018;26(2):178-183. doi: 10.1080/09273948.2017.1381272. Epub 2017 Oct 26.
PURPOSE
To analyze and compare the clinical profile of herpes zoster ophthalmicus (HZO) patients in a South Indian patient population aged <60 years and ≥60 years and determine the risk factors for recurrence of ocular inflammation.
METHODS
Retrospective study of 249 cases between 2006 and 2016 from two tertiary referral eye centres in south india.
RESULTS
Out of 249 cases, 189 cases were <60 years (Group 1) and 60 cases were aged ≥60 years (Group2). Presence of diabetes mellitus, increased intraocular pressure(IOP) at the time of active inflammation, use of topical steroids and recurrences were significantly more common in group 1. Significant risk factors for recurrences included corneal, uveal, scleral involvements and increase in IOP. Good vision at presentation was noted in 67.9% of the patients.
CONCLUSIONS
Anterior uveitis with or without keratitis was the most common presentation observed in more than 50% cases. The overall visual outcome was good.
目的
分析和比较年龄<60 岁和≥60 岁的印度南部患者人群中带状疱疹性眼病（HZO）患者的临床特征，并确定眼部炎症复发的危险因素。
方法
回顾性分析了 2006 年至 2016 年间来自印度南部两个三级转诊眼科中心的 249 例病例。
结果
在 249 例病例中，189 例年龄<60 岁（第 1 组），60 例年龄≥60 岁（第 2 组）。第 1 组中糖尿病、炎症活动时眼内压（IOP）升高、局部皮质类固醇使用和复发的发生率明显更高。复发的显著危险因素包括角膜、葡萄膜、巩膜受累和 IOP 升高。在就诊时，67.9%的患者视力良好。
结论
50%以上的患者最常见的表现为前葡萄膜炎伴或不伴角膜炎。总体视觉预后良好。
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