Fernández de Casadevante Victoria, Cantarero-Arévalo Lourdes, Gil Cuesta Julita, Valentiner-Branth Palle
Infectious Disease Epidemiology, Statens Serum Institut, Artillerivej 5 2300 København S, Copenhagen, Denmark; Section for Social and Clinical Pharmacy, Department of Pharmacy, Section for Social and Clinical Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Section for Social and Clinical Pharmacy, Department of Pharmacy, Section for Social and Clinical Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Papillomavirus Res. 2016 Dec;2:78-84. doi: 10.1016/j.pvr.2016.03.003. Epub 2016 Apr 14.
We examined ethnicity-related differences in the uptake of a temporary free-of-charge HPV vaccine (HPVV) catch-up programme offered in Denmark from August 2012 to December 2013 to women born from 1985-1992 and compared it with the previous self-payment system in place.
We conducted a nationwide retrospective cohort study. We performed logistic regression analyses to examine the relationship between ethnic background and HPV vaccine (HPVV) programme initiation.
The free programme increased the vaccination uptake from 16% to 75%. Descendants (Denmark-born women with both parents of foreign origin) and immigrants in Denmark for more than 5 years were less likely to initiate the free HPVV programme than Denmark-born women ((aOR=0.56; 95% CI: 0.54-0.59) and (aOR=0.39; 95% CI: 0.38-0.40), respectively). The likelihood of HPVV programme initiation among immigrants increased with time in Denmark ((aOR=2.28; 95% CI: 2.11-2.48) for immigrants living in Denmark for 16-20 years compared to 6-10 years)).
The initiation of the free-of-charge HPVV programme was satisfactory. However, large differences in uptake were demonstrated, indicating that some target groups are harder to reach than others. The integration process (as related to use of health services) occurs over many years where differences between the different population groups seem to vanish.
我们研究了2012年8月至2013年12月在丹麦为1985年至1992年出生的女性提供的临时免费人乳头瘤病毒疫苗（HPV疫苗）补种计划中与种族相关的差异，并将其与之前的自费系统进行了比较。
我们开展了一项全国性回顾性队列研究。我们进行了逻辑回归分析，以研究种族背景与HPV疫苗（HPV疫苗）计划启动之间的关系。
免费计划使疫苗接种率从16%提高到了75%。后代（父母双方均为外国血统的丹麦出生女性）和在丹麦居住超过5年的移民比丹麦出生的女性启动免费HPV疫苗计划的可能性更小（调整后比值比分别为0.56；95%置信区间：0.54 - 0.59）和（调整后比值比为0.39；95%置信区间：0.38 - 0.40）。移民中启动HPV疫苗计划的可能性随在丹麦居住时间的增加而增加（与居住6 - 10年的移民相比，居住16 - 20年的移民调整后比值比为2.28；95%置信区间：2.11 - 2.48）。
免费HPV疫苗计划的启动情况令人满意。然而，接种率存在很大差异，这表明一些目标群体比其他群体更难覆盖到。整合过程（与卫生服务利用相关）需要多年时间，不同人群之间的差异似乎会逐渐消失。
