Department of Emergency Medicine, University Hospital Basel, Petersgraben 2, CH-4031 Basel, Switzerland.
Department of Emergency Medicine, University Hospital Basel, Petersgraben 2, CH-4031 Basel, Switzerland.
Eur J Intern Med. 2017 Nov;45:8-12. doi: 10.1016/j.ejim.2017.09.013. Epub 2017 Oct 23.
It is known that symptoms are predictive of mortality in "nonsurgical" emergency patients. It is unknown whether a prospective, systematic, and "unscreened" assessment of all symptoms is of any prognostic value. Therefore, we aimed to examine the association between symptoms and outcomes in an all-comer population.
Data were acquired during 6weeks at the ED of the University Hospital Basel, a tertiary hospital. Consecutive patients presenting to the ED were included. Symptoms at presentation were systematically assessed using a comprehensive questionnaire.
A consecutive sample of 3960 emergency patients with a median age of 51years (51.7% male) was studied. The median number of symptoms was two. In the group of patients with the most prevalent symptoms, the median number of symptoms ranged between two and five. Overall, hospitalisation rate was 31.2%, referral to intensive care was 5.5%, in-hospital-mortality was 1.4%, and one-year mortality was 5.8%. In-hospital mortality ranged from 0% to 4.3%, and one-year mortality from 0% to 14.4% depending on the presenting symptoms. Dyspnoea and weakness were significant predictors of one-year mortality (14.4% and 9.2%, respectively).
Most emergency patients indicated two or more symptoms. Systematically assessed symptoms at presentation can be used for prediction of outcomes. While dyspnoea is a known predictor, weakness has not been identified as predictor of mortality before. This knowledge could be used to improve risk stratification- thereby reducing the risk of adverse outcomes.
众所周知,症状可预测“非手术”急诊患者的死亡率。目前尚不清楚是否对所有症状进行前瞻性、系统性和“无筛选”评估具有任何预后价值。因此,我们旨在研究所有患者人群中症状与结局之间的关联。
本研究数据采集于巴塞尔大学医院急诊科的 6 周时间内,该医院是一家三级医院。连续纳入到急诊科就诊的患者。使用综合问卷系统评估就诊时的症状。
研究纳入了连续 3960 例急诊患者,中位年龄为 51 岁(51.7%为男性)。中位症状数为 2 个。在症状最常见的患者组中,症状中位数在 2 到 5 之间。总体而言,住院率为 31.2%,转入重症监护病房率为 5.5%,院内死亡率为 1.4%,1 年死亡率为 5.8%。院内死亡率范围为 0%至 4.3%,1 年死亡率范围为 0%至 14.4%,取决于就诊时的症状。呼吸困难和虚弱是 1 年死亡率的显著预测因素(分别为 14.4%和 9.2%)。
大多数急诊患者表示有两个或更多症状。就诊时系统评估的症状可用于预测结局。虽然呼吸困难是已知的预测因素,但虚弱以前尚未被确定为死亡的预测因素。这些知识可用于改善风险分层,从而降低不良结局的风险。