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来自一名乳糜泻患者十二指肠黏膜的菌株CD08_4的基因组序列。

Genome Sequence of Strain CD08_4, an Isolate from the Duodenal Mucosa of a Celiac Disease Patient.

作者信息

Chander Atul Munish, Kumari Munesh, Kochhar Rakesh, Dhawan Devinder Kumar, Bhadada Sanjay Kumar, Mayilraj Shanmugam

机构信息

Department of Biophysics, Panjab University, Chandigarh, India.

Department of Endocrinology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

出版信息

Genome Announc. 2017 Oct 26;5(43):e01158-17. doi: 10.1128/genomeA.01158-17.

Abstract

We report here the 3.8-Mb genome sequence of strain CD08_4, an isolate from the duodenal mucosa of a celiac disease patient. The genome consists of specific virulence determinant genes, antibiotic resistance genes, genes for coping with oxidative stress, and genes responsible for iron acquisition and metabolism, suggestive of its pathogenic attributes.

摘要

我们在此报告菌株CD08_4的380万个碱基对的基因组序列,该菌株分离自一名乳糜泻患者的十二指肠黏膜。该基因组由特定的毒力决定基因、抗生素抗性基因、应对氧化应激的基因以及负责铁获取和代谢的基因组成,表明其具有致病特性。

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