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经腹腹膜前修补术与开放修补术治疗原发性单侧腹股沟疝的Meta分析

Transabdominal Pre-Peritoneal Versus Open Repair for Primary Unilateral Inguinal Hernia: A Meta-analysis.

作者信息

Wu James J, Way Joshua A, Eslick Guy D, Cox Michael R

机构信息

Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.

The Whiteley-Martin Research Centre, Nepean Hospital, Penrith, NSW, Australia.

出版信息

World J Surg. 2018 May;42(5):1304-1311. doi: 10.1007/s00268-017-4288-9.

DOI:10.1007/s00268-017-4288-9
PMID:29075859
Abstract

BACKGROUND

Recent NICE guidelines recommend open surgical approaches for the treatment of primary unilateral inguinal hernias. However, many surgeons perform a laparoscopic approach based on the advantages of less post-operative pain and faster recovery. Our aim was to examine current evidence comparing transabdominal pre-peritoneal (TAPP) laparoscopic repair and open surgical repair for primary inguinal hernias.

METHODS

A systematic search of six electronic databases was conducted for randomised controlled trials (RCTs) comparing TAPP and open repair for primary unilateral inguinal hernia. A random-effects model was used to combine the data.

RESULTS

A total of 13 RCTs were identified, with 1310 patients receiving TAPP repair and 1331 patients receiving open repair. There was no significant difference between the two groups for rates of haematoma (RR 0.92; 95% CI 0.49-1.71; P = 0.78), seroma (RR 1.90; 95% CI 0.87-4.14; P = 0.10), urinary retention (RR 0.99; 95% CI 0.36-2.76; P = 0.99), infection (RR 0.61; 95% CI 0.29-1.28; P = 0.19), and hernia recurrence (RR 0.67; 95% CI 0.42-1.07; P = 0.10). TAPP repair had a significantly lower rate of paraesthesia (RR 0.20; 95% CI 0.08-0.50; P = 0.0005), shorter bed stay (2.4 ± 1.4 vs 3.1 ± 1.6 days, P = 0.0006), and shorter return to normal activities (9.5 ± 7.9 vs 17.3 ± 8.4 days, P < 0.00001).

CONCLUSIONS

Our findings demonstrated that TAPP repair did not have higher rate of morbidity or hernia recurrence and is an equivalent approach to open repair, with the advantages of faster recovery and reduced paraesthesia.

摘要

背景

英国国家卫生与临床优化研究所(NICE)近期发布的指南推荐采用开放手术方法治疗原发性单侧腹股沟疝。然而,许多外科医生基于术后疼痛较轻和恢复较快的优势,选择腹腔镜手术方法。我们的目的是研究比较经腹腹膜前(TAPP)腹腔镜修补术与开放手术修补术治疗原发性腹股沟疝的现有证据。

方法

对六个电子数据库进行系统检索,以查找比较TAPP与开放修补术治疗原发性单侧腹股沟疝的随机对照试验(RCT)。采用随机效应模型合并数据。

结果

共识别出13项RCT,其中1310例患者接受TAPP修补术,1331例患者接受开放修补术。两组在血肿发生率(RR 0.92;95%CI 0.49 - 1.71;P = 0.78)、血清肿发生率(RR 1.90;95%CI 0.87 - 4.14;P = 0.10)、尿潴留发生率(RR 0.99;95%CI 0.36 - 2.76;P = 0.99)、感染发生率(RR 0.61;95%CI 0.29 - 1.28;P = 0.19)和疝复发率(RR 0.67;95%CI 0.42 - 1.07;P = 0.10)方面无显著差异。TAPP修补术的感觉异常发生率显著较低(RR 0.20;95%CI 0.08 - 0.50;P = 0.0005),住院时间较短(2.4 ± 1.4天对3.1 ± 1.6天,P = 0.0006),恢复正常活动的时间较短(9.5 ± 7.9天对17.3 ± 8.4天,P < 0.00001)。

结论

我们的研究结果表明,TAPP修补术的发病率或疝复发率并不更高,是一种与开放修补术等效的方法,具有恢复更快和感觉异常减少的优势。

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