Krok-Schoen Jessica L, Adams Ingrid K, Baltic Ryan D, Fisher James L
Division of Medical Dietetics and Health Sciences, School of Health and Rehabilitation Sciences, College of Medicine, The Ohio University, Columbus, OH, USA.
Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
Ethn Health. 2020 Jan;25(1):79-92. doi: 10.1080/13557858.2017.1395818. Epub 2017 Oct 27.
To examine potential ethnic disparities in cancer incidence and survival rates among the oldest old using data from the SEER Program. Cases diagnosed with one of the leading four cancer sites (lung and bronchus, colon and rectum, female breast, prostate) and four cancer sites (stomach, liver and intrahepatic bile duct, gallbladder, and cervical) that disproportionally affect Hispanics were reported to one of 18 SEER registries. Differences in cancer incidence were examined for cases aged ≥85 years diagnosed during the most recent 5-year time period (2009-2013) and, to examine changes over time, from 1992 to 2013. Five-year relative cancer survival probability was examined for Hispanics and non-Hispanics aged ≥85 years diagnosed 2006-2012. From 2009 to 2013, non-Hispanics aged ≥85 years had higher incidence rates compared to Hispanics for colon and rectum, lung and bronchus, female breast, and prostate cancers. Five-year survival probability for cancers of all stages combined was higher for non-Hispanics than Hispanics in this age group. However, Hispanics had higher survival probability of colon and rectum and lung and bronchus cancers diagnosed at regional (colon and rectum: 67.2% vs. 60.5%; lung and bronchus: 15.9% vs. 12.7%) and distant (colon and rectum: 5.4% vs. 3.8%; lung and bronchus: 2.8% vs. 2.2%) stages than non-Hispanics, respectively. Ethnic differences in cancer incidence and survival probability exist for the ≥85 population. Continued efforts are needed to understand and reduce ethnic disparities in cancer prevention and treatment for this population.
利用监测、流行病学和最终结果（SEER）项目的数据，研究最年长者中癌症发病率和生存率方面潜在的种族差异。被诊断患有四大主要癌症部位（肺和支气管、结肠和直肠、女性乳腺癌、前列腺癌）之一以及对西班牙裔影响较大的四个癌症部位（胃、肝和肝内胆管、胆囊、子宫颈）的病例，被报告给18个SEER登记处之一。对在最近5年期间（2009 - 2013年）诊断出的年龄≥85岁的病例的癌症发病率差异进行了研究，并且为了研究随时间的变化，还研究了1992年至2013年期间的情况。对2006 - 2012年期间诊断出的年龄≥85岁的西班牙裔和非西班牙裔人群的五年相对癌症生存概率进行了研究。2009年至2013年期间，年龄≥85岁的非西班牙裔在结肠和直肠癌、肺和支气管癌、女性乳腺癌以及前列腺癌方面的发病率高于西班牙裔。在这个年龄组中，所有阶段癌症合并的五年生存概率非西班牙裔高于西班牙裔。然而，西班牙裔在区域阶段（结肠和直肠：67.2%对60.5%；肺和支气管：15.9%对12.7%）和远处阶段（结肠和直肠：5.4%对3.8%；肺和支气管：2.8%对2.2%）诊断出的结肠和直肠癌以及肺和支气管癌的生存概率分别高于非西班牙裔。对于85岁及以上人群，癌症发病率和生存概率存在种族差异。需要持续努力去了解并减少该人群在癌症预防和治疗方面的种族差异。
