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前列腺特异性膜抗原 PET/CT 中表现为腹膜转移的脾种植,经脾脏 SPECT/CT 选择性检查得以确诊。

Abdominal Splenosis Mimicking Peritoneal Metastasis in Prostate-Specific Membrane Antigen PET/CT, Confirmed With Selective Spleen SPECT/CT.

机构信息

From the *Department of Nuclear Medicine, Yeditepe University School of Medicine; †Department of Nuclear Medicine, Sisli Etfal Training and Research Hospital, University of Health Sciences; ‡Department of Nuclear Medicine, Cerrahpasa Faculty of Medicine, Istanbul University; and §Department of Nuclear Medicine, Okmeydani Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

出版信息

Clin Nucl Med. 2017 Dec;42(12):e504-e505. doi: 10.1097/RLU.0000000000001878.

DOI:10.1097/RLU.0000000000001878
PMID:29076911
Abstract

Ga-prostate-specific membrane antigen (PSMA) PET/CT is a rapidly evolving diagnostic technique to image prostate cancer. In contrast to the name PSMA, various tissues show Ga-PSMA uptake in PET/CT imaging. We present a case of a 68-year-old man with prostate cancer who underwent Ga-PSMA PET/CT. Along with metastatic lymph nodes, multiple nodular lesions within the peritoneal spaces of all 4 quadrants of the abdomen showed high PSMA expression. Because of a history of splenic rupture, a Tc-labeled heat-denatured erythrocyte scintigraphy and SPECT were performed. Peritoneal lesions showed high uptake, confirming widespread peritoneal splenosis.

摘要

前列腺特异性膜抗原(PSMA)Ga-PET/CT 是一种用于前列腺癌成像的快速发展的诊断技术。与 PSMA 的名称不同,各种组织在 PET/CT 成像中都显示出 Ga-PSMA 的摄取。我们报告了一例 68 岁患有前列腺癌的男性患者,他接受了 Ga-PSMA PET/CT 检查。除了转移性淋巴结外,腹部 4 个象限的腹膜腔内的多个结节性病变也显示出 PSMA 高表达。由于脾破裂的病史,进行了 Tc 标记的热变性红细胞闪烁显像和 SPECT。腹膜病变显示出高摄取,证实了广泛的腹膜脾种植。

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