Parodi Maurizio Battaglia, Romano Francesco, Montagna Marco, Bandello Francesco
Department of Ophthalmology, Vita-Salute University, Ospedale San Raffaele, Milan - Italy.
Eur J Ophthalmol. 2018 Mar;28(2):251-252. doi: 10.5301/ejo.5001056.
To describe a case of rubella retinopathy complicated by bilateral choroidal neovascularization (CNV) and late development of large choroidal excavation (LCE).
A 19-year-old woman with a diagnosis of rubella retinopathy underwent her annual ophthalmologic examination, including visual acuity testing and slit-lamp biomicroscopy with dilated fundus examination. Color fundus photography, spectral-domain optical coherence tomography (SD-OCT) scans, and optical coherence tomography angiography were acquired to complete the investigation of her ocular condition. The main findings are described in this case report.
This woman came to our attention in 2010 with a history of rubella retinopathy, complicated by bilateral CNV and treated with photodynamic therapy (PDT) in 2006. After 6 years of annual follow-up examinations, her visual acuity remained stable in both eyes (20/100), whereas SD-OCT scans uncovered the development of a bilateral LCE in the macular area, associated with a macular hole in the right eye. Optical coherence tomography angiography revealed a vascular network surrounding the choroidal excavation.
Large choroidal excavation is a rare finding that has been described in few chorioretinal diseases, e.g., North Carolina macular dystrophy and toxoplasmosis. We propose to include rubella retinopathy complicated by CNV in the differential diagnosis of LCE, although we recognize the possibility that PDT might have induced or facilitated its formation.
描述一例风疹性视网膜病变合并双侧脉络膜新生血管(CNV)及晚期出现大脉络膜凹陷(LCE)的病例。
一名诊断为风疹性视网膜病变的19岁女性接受年度眼科检查,包括视力测试、散瞳眼底检查的裂隙灯生物显微镜检查。进行彩色眼底照相、光谱域光学相干断层扫描(SD - OCT)及光学相干断层扫描血管造影以全面评估其眼部状况。本病例报告描述了主要发现。
该女性于2010年引起我们注意,有风疹性视网膜病变病史,合并双侧CNV,并于2006年接受光动力疗法(PDT)治疗。经过6年的年度随访检查,她双眼视力保持稳定(20/100),而SD - OCT扫描发现黄斑区出现双侧LCE,右眼伴有黄斑裂孔。光学相干断层扫描血管造影显示脉络膜凹陷周围有血管网络。
大脉络膜凹陷是一种罕见的发现,在少数脉络膜视网膜疾病中有所描述,如北卡罗来纳黄斑营养不良和弓形虫病。我们建议在LCE的鉴别诊断中纳入合并CNV的风疹性视网膜病变,尽管我们认识到PDT可能诱导或促进了其形成。