光动力疗法治疗风疹性视网膜病变继发脉络膜新生血管化
Photodynamic therapy for the treatment of choroidal neovascularization secondary to rubella retinopathy.
作者信息
Wang Leo K, Kansal Sukesh, Pulido Jose S
机构信息
Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago Eye and Ear Infirmary, Chicago, Illinois 60612, USA.
出版信息
Am J Ophthalmol. 2002 Nov;134(5):790-2. doi: 10.1016/s0002-9394(02)01647-1.
PURPOSE
To describe a patient for whom photodynamic therapy was used to treat subfoveal choroidal neovascularization secondary to rubella retinopathy.
DESIGN
Interventional case report.
METHODS
A 36-year-old man with subfoveal choroidal neovascularization secondary to rubella retinopathy was treated with photodynamic therapy using verteporfin. Outcome was followed up with subsequent fundus examinations, fluorescein angiography, and evaluations of best-corrected visual acuity.
RESULTS
Two treatments of photodynamic therapy using verteporfin resulted in involution of the neovascular membrane, resolution of subretinal hemorrhage, and improvement in best-corrected visual acuity from 20/200 to 20/60 2 months after the second treatment. Owing to recurrence of active choroidal neovascularization, the patient required two more treatments of photodynamic therapy in the next 6 months, after which his best-corrected visual acuity was restored to 20/60.
CONCLUSION
Photodynamic therapy may be an effective treatment for subfoveal choroidal neovascularization secondary to rubella retinopathy.
目的
描述一名采用光动力疗法治疗风疹性视网膜病变继发的黄斑下脉络膜新生血管的患者。
设计
介入性病例报告。
方法
一名患有风疹性视网膜病变继发黄斑下脉络膜新生血管的36岁男性患者，采用维替泊芬进行光动力治疗。通过后续的眼底检查、荧光素血管造影以及最佳矫正视力评估来跟踪治疗结果。
结果
两次使用维替泊芬的光动力治疗使新生血管膜消退，视网膜下出血吸收，最佳矫正视力在第二次治疗后2个月从20/200提高到20/60。由于活动性脉络膜新生血管复发，患者在接下来的6个月内又接受了两次光动力治疗，之后其最佳矫正视力恢复到20/60。
结论
光动力疗法可能是治疗风疹性视网膜病变继发黄斑下脉络膜新生血管的有效方法。
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