Navarro-Díaz Francisco José, Amillo Mónica, Rosales María, Panadero Ana, Ena Javier
Servicio de Urgencias, Hospital Marina Baixa, Villajoyosa, Alicante, España.
Servicio de Medicina Interna, Hospital Marina Baixa, Villajoyosa, Alicante, España.
Emergencias. 2015 Feb;27(1):39-42.
To identify opportunities to improve the care of adult patients with diabetic ketoacidosis in the emergency room.
Retrospective observational study of records for 2010 to 2013. Searching for International Classification of Diseases discharge codes 250.1–250.3 we identified patients who met the following 3 criteria: ketonuria of 100 mg/dL or more, diagnosed diabetes or glucose concentration of 250 mg/dL or more, and venous blood pH below 7.30 (or venous bicarbonate concentration less than 18 mEq/L). We reviewed the cases to extract patient and clinical characteristics and time from triage until diagnosis and start of treatment. The findings were compared with recommendations in clinical practice guidelines.
We identified 49 episodes of diabetic ketoacidosis (4 mild, 32 moderate, and 13 severe) in 43 patients. The median delay between triage until the first blood test results were available was 142 minutes (range, 59-597 minutes). In 50% of the cases fluid therapy was delayed beyond the time recommended in clinical practice guidelines. Intravenous insulin was also delayed (in 66%) and insuficient intravenous potassium was given in 65%. Sodium bicarbonate was overused (in 50%). Half the patients developed hypokalemia in the hospital.
Diagnosis and initiation of treatment were often delayed for patients with diabetic ketoacidosis in our emergency department.
确定改善急诊室成年糖尿病酮症酸中毒患者护理的机会。
对2010年至2013年的记录进行回顾性观察研究。通过查找国际疾病分类出院编码250.1 - 250.3,我们确定了符合以下3项标准的患者:尿酮体100mg/dL或更高、已确诊糖尿病或血糖浓度250mg/dL或更高、静脉血pH低于7.30(或静脉血碳酸氢盐浓度低于18mEq/L)。我们回顾这些病例以提取患者和临床特征以及从分诊到诊断和开始治疗的时间。将研究结果与临床实践指南中的建议进行比较。
我们在43例患者中确定了49次糖尿病酮症酸中毒发作(4例轻度、32例中度和13例重度)。从分诊到获得首次血液检测结果的中位延迟时间为142分钟(范围为59 - 597分钟)。在50%的病例中,液体治疗延迟超过了临床实践指南推荐的时间。静脉注射胰岛素也有延迟(66%),并且65%的患者静脉补钾不足。碳酸氢钠使用过度(50%)。一半的患者在住院期间出现低钾血症。
在我们的急诊科,糖尿病酮症酸中毒患者的诊断和治疗启动常常延迟。