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肋骨骨折手术固定最佳时机的多中心评估

A multicenter evaluation of the optimal timing of surgical stabilization of rib fractures.

作者信息

Pieracci Fredric M, Coleman Julia, Ali-Osman Francis, Mangram Alicia, Majercik Sarah, White Thomas W, Jeremitsky Elan, Doben Andrew R

机构信息

From the Denver Health Medical Center (F.M.P., J.C.), Denver, Colorado; Honor Health (F.A.-O., A.M.), Pheonix, Arizona; Intermountain Medical Center (S.M., T.W.W.), Salt Lake City, Utah; and Baystate Medical Center (E.J., A.R.D.), Springfield, Massachusetts.

出版信息

J Trauma Acute Care Surg. 2018 Jan;84(1):1-10. doi: 10.1097/TA.0000000000001729.

Abstract

BACKGROUND

The optimal timing of surgical stabilization of rib fractures (SSRF) remains debated. We hypothesized that (1) demographic, radiologic, and clinical variables are associated with time to surgery and (2) shorter time to SSRF improves acute outcomes.

METHODS

Prospectively collected SSRF databases from four trauma centers were merged and analyzed (2006-2016). The independent variable was days from hospital admission to SSRF (early [<1 day], mid [1-2 days], and late [3-10 days]). Outcomes included length of operation, number of ribs repaired, prolonged (>24 hours) mechanical ventilation, pneumonia, tracheostomy, length of stay, and mortality. Multivariable logistic regression was used to control for significant differences in covariates between groups.

RESULTS

Five hundred fifty-one patients were analyzed. The median time to SSRF was 1 day (range, 0-10); 207 (37.6%) patients were in the early group, 168 (30.5%) in the midgroup, and 186 (31.9%) in the late group. There was a significant shift toward earlier SSRF over the study period. Time to SSRF was significantly associated with study center (p < 0.01), year of surgery (p < 0.01), age (p = 0.02), mechanism of injury (p = 0.04), and body mass index (p = 0.02). Injury severity was not associated with time to surgery. Despite repairing the same median number of ribs (4; range, 1-13), median length of surgery was 68 minutes longer for the late as compared to the early group (p < 0.01). After controlling for the aforementioned significant covariates, each additional hospital day before SSRF was independently associated with a 31% increased likelihood of pneumonia (p < 0.01), a 27% increased likelihood of prolonged mechanical ventilation (p < 0.01), and a 26% increased likelihood of tracheostomy (p < 0.01).

CONCLUSION

Surgical stabilization of rib fractures within 1 day of admission is associated with certain demographic and physiologic variables. After controlling for confounding factors, early SSRF was accomplished using less operative time, and was associated with favorable outcomes. When indicated and feasible, SSRF should occur as early as possible.

LEVEL OF EVIDENCE

Therapy, level III.

摘要

背景

肋骨骨折手术固定(SSRF)的最佳时机仍存在争议。我们假设:(1)人口统计学、放射学和临床变量与手术时间相关;(2)缩短至SSRF的时间可改善急性预后。

方法

合并并分析了前瞻性收集的来自四个创伤中心的SSRF数据库(2006 - 2016年)。自变量为从入院到SSRF的天数(早期[<1天]、中期[1 - 2天]和晚期[3 - 10天])。结局包括手术时长、修复肋骨数量、机械通气延长(>24小时)、肺炎、气管切开术、住院时长和死亡率。采用多变量逻辑回归来控制组间协变量的显著差异。

结果

分析了551例患者。至SSRF的中位时间为1天(范围0 - 10天);早期组207例(37.6%),中期组168例(30.5%),晚期组186例(31.9%)。在研究期间,SSRF有显著提前的趋势。至SSRF的时间与研究中心(p < 0.01)、手术年份(p < 0.01)、年龄(p = 0.02)、损伤机制(p = 0.04)和体重指数(p = 0.02)显著相关。损伤严重程度与手术时间无关。尽管修复的肋骨中位数量相同(4根;范围1 - 13根),但晚期组的手术中位时长比早期组长68分钟(p < 0.01)。在控制上述显著协变量后,在SSRF前每增加一天住院时间,肺炎发生的可能性独立增加31%(p < 0.01),机械通气延长的可能性增加27%(p < 0.01),气管切开术的可能性增加26%(p < 0.01)。

结论

入院1天内进行肋骨骨折手术固定与特定的人口统计学和生理学变量相关。在控制混杂因素后,早期SSRF手术时间更短,且与良好的预后相关。在有指征且可行的情况下,SSRF应尽早进行。

证据级别

治疗,III级。

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