Wilson Mara Lynn
Department of Endocrine Neoplasia and Hormonal Disorder, MD Anderson Cancer Center, 1400 Pressler Street, Room FCT 12.5039.02, Houston, TX 77030-3722, USA.
Nurs Clin North Am. 2017 Dec;52(4):665-677. doi: 10.1016/j.cnur.2017.07.011. Epub 2017 Oct 5.
Prediabetes is a complex multifactorial metabolic disorder that extends beyond glucose control. Current studies have found that microvascular disease (neuropathy, nephropathy, and retinopathy), macrovascular disease (stroke, coronary artery disease, and peripheral vascular disease), periodontal disease, cognitive dysfunction, blood pressure changes, obstructive sleep apnea, low testosterone level, fatty liver disease, and cancer are some of conditions that are present with the onset of glycemic dysregulation. The presence of prediabetes increases the risk of developing type 2 diabetes 3-fold to 10-fold. The identification and treatment of prediabetes are imperative to prevent or delay the progression to type 2 diabetes.
糖尿病前期是一种复杂的多因素代谢紊乱疾病，其影响范围超出了血糖控制。目前的研究发现，微血管疾病（神经病变、肾病和视网膜病变）、大血管疾病（中风、冠状动脉疾病和外周血管疾病）、牙周疾病、认知功能障碍、血压变化、阻塞性睡眠呼吸暂停、低睾酮水平、脂肪肝疾病和癌症等，都是血糖调节异常开始时出现的一些病症。糖尿病前期的存在会使患2型糖尿病的风险增加3至10倍。识别和治疗糖尿病前期对于预防或延缓向2型糖尿病的进展至关重要。
