Kimata Takahisa, Kino Jiro, Yamanouchi Sohsaku, Suruda Chikushi, Tsuji Shoji, Kaneko Kazunari
Department of Pediatrics, Kansai Medical University, Osaka, Japan.
Pediatr Int. 2017 Oct;59(10):1109-1111. doi: 10.1111/ped.13375.
In parallel with the increase in the prevalence of childhood chronic diseases, the rate of cesarean delivery has risen during the past decades. This study tested the hypothesis that children delivered by cesarean section (CS) have a higher risk of relapse of idiopathic nephrotic syndrome (INS). Fifty-six children with INS were categorized into three groups. Group A consisted of patients with INS who had no relapses after the onset of INS; group B consisted of patients with INS who had infrequent relapse; and group C consisted of patients with INS who had frequent relapse. The number of enrolled patients in groups A, B, and C was 10, 14, and 32, respectively. The ratio of neonates delivered via CS was significantly higher in group C (37.5%, P < 0.001) than in groups A (0%) and B (7.1%). This study shows that CS is associated with an increased risk of relapse of childhood INS.
在儿童慢性病患病率上升的同时，剖宫产率在过去几十年中也有所上升。本研究检验了剖宫产（CS）分娩的儿童患特发性肾病综合征（INS）复发风险更高的假设。56例INS患儿被分为三组。A组为INS发病后未复发的患者；B组为INS复发不频繁的患者；C组为INS复发频繁的患者。A、B、C三组入组患者人数分别为10例、14例和32例。C组经CS分娩的新生儿比例（37.5%，P<0.001）显著高于A组（0%）和B组（7.1%）。本研究表明，CS与儿童INS复发风险增加有关。
