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[对接触肾毒性物质的受试者的损伤评估]

[Evaluation of damage in subjects exposed to nephrotoxic substances].

作者信息

Tranchina G, Totaro S, Lo Cascio N, Scaglione C, Picciotto D, Caizza R, La Porta V

机构信息

Istituto di Medicina del Lavoro e Preventiva dell'Università degli Studi di Palermo.

出版信息

G Ital Med Lav. 1988 Mar;10(2):77-9.

PMID:2908271
Abstract

Nephritic functionality has been studies, making use of same nephritic enzymes dosage (NAG, AAP, alpha-glucosidase, lysozyme) in three groups of workers (varnishers, metallurgists, plastic manufacture employees) professionally exposed to nephritic damage, and in a control group made up of not professionally exposed to the same hazard subjects. The aim was to precociously detect possible nephritic damage, i.e. before classic nephritic functionality indexes were distorted. An increased enzymuria appeared in those subjects that were exposed to nephrotoxic hazard. Increased enzymuria have been found in only one subject of the control group. We deem it should be useful, to customarily measure out nephritic enzymes as trusted index of tabular damage, in hiring and pensionary control examinations.

摘要

已对肾功进行了研究,在三组职业性接触肾损伤的工人(清漆工、冶金工人、塑料制造员工)以及由未职业性接触相同危害的受试者组成的对照组中,使用相同剂量的肾酶(NAG、AAP、α - 葡萄糖苷酶、溶菌酶)。目的是在经典的肾功能指标出现异常之前,尽早发现可能的肾损伤。接触肾毒性危害的受试者出现了酶尿增加的情况。在对照组中仅一名受试者发现酶尿增加。我们认为,在招聘和退休体检中,常规检测肾酶作为可靠的肾小管损伤指标应是有用的。

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1
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