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Ugi Multicomponent Reaction Based Synthesis of Medium-Sized Rings.
Org Lett. 2017 Nov 17;19(22):6176-6179. doi: 10.1021/acs.orglett.7b03094. Epub 2017 Oct 30.
2
Polymacrocycles Derived via Ugi Multi-Component Reactions.
Macromol Rapid Commun. 2019 Feb;40(4):e1800748. doi: 10.1002/marc.201800748. Epub 2018 Nov 20.
3
Two-Step Macrocycle Synthesis by Classical Ugi Reaction.
J Org Chem. 2018 Feb 2;83(3):1441-1447. doi: 10.1021/acs.joc.7b02984. Epub 2018 Jan 24.
4
Versatile Multicomponent Reaction Macrocycle Synthesis Using α-Isocyano-ω-carboxylic Acids.
Org Lett. 2015 Oct 16;17(20):4980-3. doi: 10.1021/acs.orglett.5b02419. Epub 2015 Oct 6.
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Two-Step Synthesis of Complex Artificial Macrocyclic Compounds.
Angew Chem Int Ed Engl. 2017 Aug 28;56(36):10725-10729. doi: 10.1002/anie.201704426. Epub 2017 Aug 1.
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Ammonia-Promoted One-Pot Tetrazolopiperidinone Synthesis by Ugi Reaction.
ACS Comb Sci. 2017 May 8;19(5):343-350. doi: 10.1021/acscombsci.7b00033. Epub 2017 Mar 8.
7
Single-step Ugi multicomponent reaction for the synthesis of phosphopeptidomimetics.
J Org Chem. 2013 Oct 18;78(20):10077-87. doi: 10.1021/jo401372x. Epub 2013 Oct 8.
9
Rapid generation of macrocycles with natural-product-like side chains by multiple multicomponent macrocyclizations (MiBs).
Org Biomol Chem. 2008 May 21;6(10):1787-95. doi: 10.1039/b715393g. Epub 2008 Mar 28.

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Multicomponent Macrocyclic IL-17a Modifier.
ACS Med Chem Lett. 2022 Aug 12;13(9):1468-1471. doi: 10.1021/acsmedchemlett.2c00257. eCollection 2022 Sep 8.
5
Design of indole- and MCR-based macrocycles as p53-MDM2 antagonists.
Beilstein J Org Chem. 2019 Feb 20;15:513-520. doi: 10.3762/bjoc.15.45. eCollection 2019.

本文引用的文献

1
Two-Step Synthesis of Complex Artificial Macrocyclic Compounds.
Angew Chem Int Ed Engl. 2017 Aug 28;56(36):10725-10729. doi: 10.1002/anie.201704426. Epub 2017 Aug 1.
2
How Big Is Too Big for Cell Permeability?
J Med Chem. 2017 Mar 9;60(5):1662-1664. doi: 10.1021/acs.jmedchem.7b00237. Epub 2017 Feb 24.
3
Artificial Macrocycles by Ugi Reaction and Passerini Ring Closure.
J Org Chem. 2016 Oct 7;81(19):8789-8795. doi: 10.1021/acs.joc.6b01430. Epub 2016 Sep 15.
4
Medium-Ring Nitrogen Heterocycles through Migratory Ring Expansion of Metalated Ureas.
Angew Chem Int Ed Engl. 2016 Sep 5;55(37):11153-7. doi: 10.1002/anie.201605714. Epub 2016 Jul 21.
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Central Nervous System Multiparameter Optimization Desirability: Application in Drug Discovery.
ACS Chem Neurosci. 2016 Jun 15;7(6):767-75. doi: 10.1021/acschemneuro.6b00029. Epub 2016 Apr 4.
6
Quantifying the chameleonic properties of macrocycles and other high-molecular-weight drugs.
Drug Discov Today. 2016 May;21(5):712-7. doi: 10.1016/j.drudis.2016.02.005. Epub 2016 Feb 15.
7
Versatile Multicomponent Reaction Macrocycle Synthesis Using α-Isocyano-ω-carboxylic Acids.
Org Lett. 2015 Oct 16;17(20):4980-3. doi: 10.1021/acs.orglett.5b02419. Epub 2015 Oct 6.
8
Efficient isocyanide-less isocyanide-based multicomponent reactions.
Org Lett. 2015 Apr 17;17(8):2002-5. doi: 10.1021/acs.orglett.5b00759. Epub 2015 Mar 31.
9
How proteins bind macrocycles.
Nat Chem Biol. 2014 Sep;10(9):723-31. doi: 10.1038/nchembio.1584. Epub 2014 Jul 20.
10
SnAP reagents for the one-step synthesis of medium-ring saturated N-heterocycles from aldehydes.
Nat Chem. 2014 Apr;6(4):310-4. doi: 10.1038/nchem.1878. Epub 2014 Mar 2.

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