Cuomo Roberto, Nisi Giuseppe, Grimaldi Luca, Brandi Cesare, D'Aniello Carlo
University of Siena.
Acta Biomed. 2017 Oct 23;88(3):297-301. doi: 10.23750/abm.v88i3.5737.
The high incidence of venous leg ulcers and the difficult to give a complete healing involves in an increase of costs for National Health System. Main therapies to obtain a fast healing are compressive bandages, treatment of abnormal venous flow and in-situ-strategies of wound care. Negative pressure therapy does not conventionally used, because these systems not allow the use of compression bandages. Recently the development of ultraportable devices has improved the compliance and the results.
Ten patients with venous chronic ulcer on the lower extremities were recruited for this study: all patients had venous leg ulcers from at least one year. We treated the patients with autologous partial thickness skin graft and subsequently we applied NANOVA device included in compressive bandage. We used NANOVA for fourteen days and after we made traditional medications. We submitted a questionnaire to evaluate the impact of dressing and NANOVA device in the quality of life of patients.
The device contributed to the formation of granulation tissue and increased the success rate of autologous skin graft without limiting mobility of patient. In addition to this, we have been able to perform compression bandages thanks to small size of this device. Eight ulcers healed within 90 days of medication.
We believe that ultraportable negative pressure systems are useful devices for treatment of venous leg ulcers because them allows to realize a compressive bandage without mobility limitations.
下肢静脉性溃疡的高发病率以及难以实现完全愈合增加了国家卫生系统的成本。实现快速愈合的主要治疗方法包括加压绷带、治疗异常静脉血流以及伤口护理的原位策略。负压疗法传统上并不使用,因为这些系统不允许使用加压绷带。最近,超便携式设备的发展提高了依从性和治疗效果。
本研究招募了10名下肢静脉慢性溃疡患者:所有患者的静脉性腿部溃疡均至少持续了一年。我们先用自体中厚皮片治疗患者,随后将NANOVA设备应用于加压绷带中。我们使用NANOVA设备14天,之后进行传统药物治疗。我们发放了一份问卷,以评估敷料和NANOVA设备对患者生活质量的影响。
该设备有助于肉芽组织的形成,提高了自体皮肤移植的成功率,且不限制患者的活动能力。除此之外,由于该设备体积小,我们能够进行加压绷带治疗。8处溃疡在用药90天内愈合。
我们认为超便携式负压系统是治疗下肢静脉性溃疡的有用设备,因为它能够在不限制活动能力的情况下实现加压绷带治疗。