Chidharla Anusha, Kanderi Tejaswi, Kasi Anup
UICOMP
UPMC Pinnacle
Acral erythema, also known as Palmar-plantar erythrodysesthesia (PPE), palmoplantar erythrodysesthesia, toxic erythema of the palms and soles, hand-foot syndrome (HFS), or Burgdorf reaction. Many classic chemotherapeutic agents and newer molecular-targeted therapies cause this adverse event. It is characterized by intense, painful erythema of the palms and soles that can progress to the formation of vesicles or bullae. See Chemotherapy Acral Erythema.
手足红斑，也称为掌跖红细胞生成障碍（PPE）、掌跖红细胞生成障碍、手足毒性红斑、手足综合征（HFS）或布尔格多夫反应。许多经典化疗药物和新型分子靶向疗法都会引发这种不良事件。其特征为手掌和脚底出现强烈的疼痛性红斑，可发展为水疱或大疱。参见化疗性手足红斑。
