Tran Huong T B, Du Thu T N, Phung Nhat D, Le Ninh H, Nguyen Toan B, Phan Hai T, Vo De T, Milford Edgar L, Tran Sinh N
Nephrology Division, Department of Medicine, University of Medicine and Pharmacy, 217 Hong Bang Str., Dist 5, Ho Chi Minh City, Vietnam.
Urology Department, Cho Ray Hospital, Ho Chi Minh City, Vietnam.
BMC Res Notes. 2017 Oct 30;10(1):523. doi: 10.1186/s13104-017-2847-7.
The prevalence of chronic kidney disease (CKD) in rural Vietnam is unknown. We wished to determine the prevalence of CKD and determine whether a simple questionnaire was able to detect individuals at high risk of CKD before expensive confirmatory laboratory testing.
A cross sectional study was performed. We recruited 2037 participants from 13 communes of Long An province, Vietnam, for CKD screening with urine albumin/creatinine ratio (ACR) measured by immunoturbidimetric method and serum creatinine to estimate glomerular filtration rate (eGFR). CKD was defined as either ACR ≥ 30 mg/g or eGFR < 60 ml/min/1.73 m. A two page questionnaire with 23 variables was administered to each participant with queries postulated to be correlated with risk of CKD.
Of the 2037 participants, 260 (12.76%) were found to have CKD. Five questionnaire variables (age more than 50, measured hypertension, history of diabetes, history of hypertension, and history of a low salt diet) were correlated with CKD, and used to construct a risk score for CKD.
CKD is common in Vietnam. Our questionnaire and risk score tool can be used to detect individuals with a higher likelihood of CKD, and who can then be more economically screened with routine laboratory confirmatory tests.
越南农村慢性肾脏病(CKD)的患病率尚不清楚。我们希望确定CKD的患病率,并确定一份简单问卷能否在进行昂贵的实验室确诊检测之前,检测出CKD高危个体。
开展了一项横断面研究。我们从越南隆安省的13个公社招募了2037名参与者,采用免疫比浊法测量尿白蛋白/肌酐比值(ACR)和血清肌酐来估算肾小球滤过率(eGFR),以进行CKD筛查。CKD的定义为ACR≥30mg/g或eGFR<60ml/min/1.73m²。向每位参与者发放一份包含23个变量的两页问卷,其中的问题被假定与CKD风险相关。
在2037名参与者中,发现260人(12.76%)患有CKD。五个问卷变量(年龄超过50岁、确诊高血压、糖尿病史、高血压病史和低盐饮食史)与CKD相关,并用于构建CKD风险评分。
CKD在越南很常见。我们的问卷和风险评分工具可用于检测CKD可能性较高的个体,然后可以通过常规实验室确诊检测进行更经济的筛查。