Adinolfi M, Rodin A, Cheetham M, Chapman M
Paediatric Research Unit, United Medical School of Guy's Hospital, London, UK.
Exp Clin Immunogenet. 1987;4(1):56-60.
A T cell subset (T4+,2H4+) has recently been identified, which acts as an inducer of T8+ suppressor cells; however 2H4 molecules have not been detected in thymuses from normal individuals or on the surface of immature thymocyte clones. In the present study, T4+,2H4+ and T8+,2H4+ cells have been found in maternal and new-born blood samples. However, only a small percentage of 2H4+ cells were detected in human fetal thymus, bone marrow, liver and spleen, thus suggesting that T cells acquire these molecules only in circulation and at a late stage of maturation.
最近已鉴定出一种T细胞亚群（T4 +，2H4 +），它作为T8 +抑制细胞的诱导剂；然而，在正常个体的胸腺中或未成熟胸腺细胞克隆的表面未检测到2H4分子。在本研究中，在母体和新生儿血液样本中发现了T4 +，2H4 +和T8 +，2H4 +细胞。然而，在人类胎儿胸腺、骨髓、肝脏和脾脏中仅检测到一小部分2H4 +细胞，因此表明T细胞仅在循环中且在成熟后期才获得这些分子。
