艾滋病毒病例管理支持服务与加纳潘唐医院抗逆转录病毒诊所接受治疗患者的CD4细胞计数改善相关。

HIV Case Management Support Service Is Associated with Improved CD4 Counts of Patients Receiving Care at the Antiretroviral Clinic of Pantang Hospital, Ghana.

作者信息

Sarfo Bismark, Vanderpuye Naa Ashiley, Addison Abigail, Nyasulu Peter

机构信息

Department of Epidemiology and Disease Control, School of Public Health, College of Health Sciences, University of Ghana, Legon, Ghana.

West Africa AIDS Foundation (WAAF), Haatso, Accra, Ghana.

出版信息

AIDS Res Treat. 2017;2017:4697473. doi: 10.1155/2017/4697473. Epub 2017 Sep 20.

DOI:10.1155/2017/4697473

PMID:29085677

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5632479/

Abstract

BACKGROUND

Factors associated with individual patient-level management of HIV have received minimal attention in sub-Saharan Africa. This study determined the association between support services and cluster of differentiation 4 (CD4) counts among HIV patients attending ART clinic in Ghana.

METHODOLOGY

This was a cross-sectional study involving adults with HIV recruited between 1 August 2014 and 31 January 2015. Data on support services were obtained through a closed-ended personal interview while the CD4 counts data were collected from their medical records. Data were entered into EpiData and analyzed using Stata software.

RESULTS

Of the 201 patients who participated in the study, 67% (129/191) received case management support service. Counseling about how to prevent the spread of HIV (crude odds ratio (cOR) (95% confidence interval (CI)) (2.79 (1.17-6.68)), mental health services (0.2 (0.04-1.00)), and case management support service (2.80 (1.34-5.82))) was associated with improved CD4 counts of 350 cells/mm or more. After adjusting for counseling about how to prevent the spread of HIV and mental health services, case management support service was significantly associated with CD4 counts of 350 cells/mm or more (aOR = 2.36 (CI = 1.01-5.49)).

CONCLUSION

Case management support service for HIV patients receiving ART improves their CD4 counts above 350 cells/mm. Incorporating HIV case management services in ART regimen should be a priority in sub-Saharan Africa.

摘要

背景

在撒哈拉以南非洲，与个体患者层面的艾滋病毒管理相关的因素很少受到关注。本研究确定了加纳接受抗逆转录病毒治疗门诊的艾滋病毒患者中支持服务与分化簇4（CD4）计数之间的关联。

方法

这是一项横断面研究，纳入了2014年8月1日至2015年1月31日招募的成年艾滋病毒感染者。通过封闭式个人访谈获取支持服务数据，同时从他们的病历中收集CD4计数数据。数据录入EpiData并使用Stata软件进行分析。

结果

在参与研究的201名患者中，67%（129/191）接受了病例管理支持服务。关于如何预防艾滋病毒传播的咨询（粗比值比（cOR）（95%置信区间（CI））（2.79（1.17 - 6.68）））、心理健康服务（0.2（0.04 - 1.00））以及病例管理支持服务（2.80（1.34 - 5.82））与CD4计数提高到350个细胞/mm³或更高相关。在对如何预防艾滋病毒传播的咨询和心理健康服务进行调整后，病例管理支持服务与CD4计数350个细胞/mm³或更高显著相关（调整后比值比 = 2.36（CI = 1.01 - 5.49））。