Dohr J, Hunzelmann N, Brown A
Klinik und Poliklinik für Dermatologie und Venerologie, Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Hautarzt. 2018 Feb;69(2):162-164. doi: 10.1007/s00105-017-4075-4.
Proton pump inhibitors (PPIs) belong to the most frequently taken drugs worldwide. Hypersensitivity to these medications is rare, but can lead to severe immediate type reactions. Especially cross-reactivity between the different PPIs can occur. In this case series, we describe 4 patients with immediate type reactions to pantoprazole and/or omeprazole.
质子泵抑制剂(PPIs)属于全球使用最为频繁的药物。对这些药物的超敏反应虽罕见,但可导致严重的速发型反应。不同质子泵抑制剂之间尤其可能发生交叉反应。在本病例系列中,我们描述了4例对泮托拉唑和/或奥美拉唑发生速发型反应的患者。